Alstoniascholarines T (1) and U (2), two novel monoterpenoid indole alkaloids from Alstonia scholaris, enabled an unexpected deuteration via activation of the sp² CH bond without any catalysts under room temperature. Structurally, alkaloid 1 represented the rare nor-C₁₇ strychnan indole, and compound 2 possessing highly modified strychnan skeleton with an additional furan ring between C-16/19. This finding presented the detailed description of natural products with sp² CH self-activation and deuteration, which may shed a light on the CH functionalization blocked by the expensive metal catalysts and/or rather harsh reaction conditions.

Alstoniascholarines T（1）和U（2），两个来自Alstonia Scholaris的新型单萜吲哚生物碱，通过在室温下活化sp ² C H键而没有任何催化剂使得出人意料的氘化。在结构上，生物碱1表示的稀有也不-C ₁₇ strychnan吲哚，和化合物2与C-19分之16之间的附加的呋喃环具有高度修饰strychnan骨架。该发现对sp ² C天然产物进行了详细描述。H的自我活化和氘化，这可能会揭示由昂贵的金属催化剂和/或相当苛刻的反应条件所阻止的C H官能化。