High throughput DNA sequencing in combination with efficient algorithms could provide the basis for a highly resolved, genome phylogeny-based and digital prokaryotic taxonomy. However, current taxonomic practice continues to rely on cumbersome journal publications for the description of new species, which still constitute the smallest taxonomic units. In response, we introduce LINbase, a web server that allows users to genomically circumscribe any group of prokaryotes with measurable DNA similarity and that uses the individual isolate as smallest unit. Since LINbase leverages the concept of Life Identification Numbers (LINs), which are codes assigned to individual genomes based on reciprocal average nucleotide identity, we refer to groups circumscribed in LINbase as LINgroups. Users can associate with each LINgroup a name, a short description, and a URL to a peer-reviewed publication. As soon as a LINgroup is circumscribed, any user can immediately identify query genomes as members and submit comments about the LINgroup. Most genomes currently in LINbase were imported from GenBank, but users can upload their own genome sequences as well. In conclusion, LINbase combines the resolution of LINs with the power of crowdsourcing in support of a highly resolved, genome phylogeny-based digital taxonomy. LINbase is available at http://www.LINbase.org.

中文翻译：

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LINbase：一种网络服务器，用于基于基因组识别原核生物作为众包生物分类的成员。

高通量DNA测序与高效算法的结合可以为高度解析的基于基因组系统发育的数字原核生物分类提供基础。但是，当前的分类学实践仍然依赖繁琐的期刊出版物来描述新物种，而新物种仍然构成了最小的分类单元。作为回应，我们引入了LINbase，这是一个网络服务器，它使用户能够通过基因组方法对具有可测量的DNA相似性的任何原核生物进行分组，并使用单个分离株作为最小单位。由于LINbase利用了生命识别号（LIN）的概念，它们是根据相互平均核苷酸同一性分配给各个基因组的代码，因此我们将LINbase中限定的组称为LINgroup。用户可以将每个LINgroup的名称，简短描述，以及经过同行评审的出版物的URL。一旦限制了LINgroup，任何用户都可以立即将查询基因组识别为成员，并提交有关LINgroup的评论。目前LINbase中的大多数基因组都是从GenBank导入的，但是用户也可以上传自己的基因组序列。总之，LINbase将LIN的分辨率与众包功能相结合，以支持高度解析的基于基因组系统发育的数字分类法。LINbase可从http://www.LINbase.org获得。LINbase将LIN的分辨率与众包能力相结合，以支持高度解析的基于基因组系统发育的数字分类法。LINbase可从http://www.LINbase.org获得。LINbase将LIN的分辨率与众包能力相结合，以支持高度解析的基于基因组系统发育的数字分类法。LINbase可从http://www.LINbase.org获得。