Enveloped viruses enter cells via a process of membrane fusion between the viral envelope and a cellular membrane. For influenza virus, mutational data have shown that the membrane-inserted portions of the hemagglutinin protein play a critical role in achieving fusion. In contrast to the relatively well-understood ectodomain, a predictive mechanistic...

中文翻译：

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流感血凝素通过两个连续的膜内机制驱动病毒进入[生物物理学和计算生物学]

包膜病毒通过病毒包膜和细胞膜之间的膜融合过程进入细胞。对于流感病毒，突变数据表明，血凝素蛋白的膜插入部分在实现融合中起关键作用。与相对容易理解的胞外域相比，预测机制...