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Treatment with convalescent plasma for critically ill patients with SARS-CoV-2 infection
Chest ( IF 9.6 ) Pub Date : 2020-07-01 , DOI: 10.1016/j.chest.2020.03.039
Bin Zhang 1 , Shuyi Liu 1 , Tan Tan 2 , Wenhui Huang 1 , Yuhao Dong 3 , Luyan Chen 1 , Qiuying Chen 1 , Lu Zhang 1 , Qingyang Zhong 4 , Xiaoping Zhang 5 , Yujian Zou 6 , Shuixing Zhang 1
Affiliation  

Abstract As of March 24, 2020, novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for 379,661 infection cases with 16,428 deaths globally and the number is still increasing rapidly. Herein, we presented four critically ill patients with SARS-CoV-2 infection who received supportive care and convalescent plasma. Although all the four patients (including a pregnant woman) recovered from SARS-CoV-2 infection eventually, randomized trials are needed to eliminate the effect of other treatments and investigate the safety and efficacy of convalescent plasma therapy.

中文翻译:

SARS-CoV-2感染危重患者的恢复期血浆治疗

摘要 截至 2020 年 3 月 24 日,新型严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 已导致全球 379,661 例感染病例,16,428 例死亡,并且该数字仍在迅速增加。在此,我们介绍了四名接受支持治疗和恢复期血浆的 SARS-CoV-2 感染重症患者。尽管所有四名患者(包括一名孕妇)最终都从 SARS-CoV-2 感染中康复,但仍需要随机试验来消除其他治疗的影响并调查恢复期血浆疗法的安全性和有效性。
更新日期:2020-07-01
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