Cervical cancer is the most common type of cancer in sub-Saharan Africa, and it is also the cancer disease that most women die from. The high mortality rate is partly due to low attendance rates to screening services and low sensitivity of visual inspection with acetic acid, which is the standard screening method used in screening programs in sub-Saharan Africa. In order to overcome of the burden of disease new screening strategies and methods are warranted. This study aims to explore the acceptability and feasibility of HPV self-sampling compared to provider-based sampling among cervical cancer screening clients living in Dar es Salaam. Women attending cervical cancer screening at Ocean Road Cancer Institute in Dar es Salaam, Tanzania between February – April 2017 were invited into the study. The participants had (1) a provider-collected sample, and (2) a self-sample for HPV on top of the regular cervical cancer screening. 50% of the participants conducted the self-sample after receiving a written instruction guide of how to collect the sample (written). The other 50% received both the written and an oral introduction to self-sampling (written+). All participants could ask for nurse assistance during self-sample collection if needed. Individual semi-structured interviews were conducted with the participants post sample collection. Data collection stopped when saturation was reached. Data were analysed using a thematic content analysis. Twenty-one women participated in the study. Regardless of how women were introduced to the self-sample (written or written+), there was a high demand for nurse presence as they felt uncertain of their personal capabilities to collect the self-sample correctly. However, as long as nurse assistance was an option most women perceived self-sampling as easy and comfortable though few experienced bleeding and pain. The majority of women preferred self-sampling over provider-sampling primarily due to the method being more private than the provider-sampling. HPV self-sampling was well-perceived and accepted, however, for the method to be feasible a nurse needed to be present. HPV Self-sampling may be an alternative method to increase uptake of cervical cancer screening. Larger quantitative studies are recommended to support the study findings.

中文翻译：

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“最好的是，您自己来做”-坦桑尼亚宫颈癌筛查客户对HPV自取样的可接受性和可行性的观点：定性的初步研究。

宫颈癌是撒哈拉以南非洲地区最常见的癌症，也是大多数女性死于癌症的疾病。死亡率高的部分原因是筛查服务的出席率低以及使用乙酸进行目视检查的敏感性低，乙酸是撒哈拉以南非洲筛查计划中使用的标准筛查方法。为了克服疾病的负担，需要新的筛选策略和方法。这项研究旨在探讨在达累斯萨拉姆的宫颈癌筛查客户中，与基于提供者的抽样相比，HPV自抽样的可接受性和可行性。2017年2月至4月之间，在坦桑尼亚达累斯萨拉姆的海洋路癌症研究所参加宫颈癌筛查的妇女被邀请参加这项研究。参与者有（1）个提供商收集的样本，（2）在常规宫颈癌筛查基础上，对HPV进行自我取样。50％的参与者在收到有关如何收集（书面）样本的书面指导后进行了自样本。另外50％的人同时接受了自我抽样的书面和口头介绍（书面+）。如果需要，所有参与者都可以在自采样期间寻求护士帮助。样本收集后，与参与者进行了个别的半结构式访谈。当达到饱和时，数据收集停止。使用主题内容分析来分析数据。21名妇女参加了这项研究。不论如何将女性介绍给自我抽样（书面或书面+），护士的存在需求很高，因为他们不确定自己能否正确收集自我样本。但是，只要可以选择护士协助，大多数妇女就认为自我采样既简单又舒适，尽管很少有人感到流血和疼痛。大多数女性更喜欢使用自我抽样而不是提供者抽样，这主要是因为该方法比提供者抽样更具私密性。HPV自采样已被很好地理解和接受，但是，要使该方法可行，需要有一名护士在场。HPV自采样可能是增加宫颈癌筛查摄取率的替代方法。建议使用较大的定量研究来支持研究结果。只要可以选择护士协助，大多数女性就认为自我采样既简单又舒适，尽管很少有人感到流血和疼痛。大多数女性更喜欢使用自我抽样而不是提供者抽样，这主要是因为该方法比提供者抽样更具私密性。HPV自采样已被很好地理解和接受，但是，要使该方法可行，需要有一名护士在场。HPV自采样可能是增加宫颈癌筛查摄取率的替代方法。建议使用较大的定量研究来支持研究结果。只要可以选择护士协助，大多数女性就认为自我采样既简单又舒适，尽管很少有人感到流血和疼痛。大多数女性更喜欢自我抽样而不是提供者抽样，这主要是因为该方法比提供者抽样更具私密性。HPV自采样已被很好地理解和接受，但是，要使该方法可行，需要有一名护士在场。HPV自采样可能是增加宫颈癌筛查摄取率的替代方法。建议使用较大的定量研究来支持研究结果。HPV自采样可能是增加宫颈癌筛查摄取率的替代方法。建议使用较大的定量研究来支持研究结果。HPV自采样可能是增加宫颈癌筛查摄取率的替代方法。建议使用较大的定量研究来支持研究结果。