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Neurocognitive functioning in patients with conversion disorder/functional neurological disorder
Journal of Neuropsychology ( IF 2.2 ) Pub Date : 2020-03-29 , DOI: 10.1111/jnp.12206
Lars de Vroege 1, 2 , Iris Koppenol 1 , Willem Johan Kop 1, 3 , Madelon M E Riem 3 , Christina Maria van der Feltz-Cornelis 4
Affiliation  

Neurocognitive symptoms are common in individuals with somatic symptom and related disorders (SSRD), but little is known about the specific impairments in neurocognitive domains in patients with conversion disorder (CD)/functional neurological disorder (FND). This study examines neurocognitive functioning in patients with CD/FND compared to patients with other SSRD. The sample consisted of 318 patients. Twenty‐nine patients were diagnosed with CD/FND, mean age 42.4, standard deviation (SD) = 13.8 years, 79.3% women, and 289 patients had other SSRD (mean age 42.1, SD = 13.3, 60.2% women). Patients completed a neuropsychological test battery that addressed a broad range of neurocognitive domains, including information processing speed, attention and executive functioning. Patients with CD/FND had clinically significant neurocognitive deficits in all neurocognitive domains based on normative data comparison. Patients with CD/FND also performed significantly worse than patients with other SSRD on information processing speed (Digit Symbol Substitution Test (V = .115, p = .035), Stroop Color–Word Test (SCWT) card 1 (V = .190, p = .006), and SCWT card 2 (V = .244, p < .001). No CD/FND vs. other SSRD differences were observed in other neurocognitive domains. These findings indicate the patients with CD/FND perform worse on information processing speed tests compared to patients with other SSRD.

中文翻译:

转换障碍/功能性神经障碍患者的神经认知功能

神经认知症状在患有躯体症状和相关疾病 (SSRD) 的个体中很常见,但对转换障碍 (CD)/功能性神经障碍 (FND) 患者的神经认知领域的特定损伤知之甚少。本研究检查了 CD/FND 患者与其他 SSRD 患者的神经认知功能。样本包括 318 名患者。29 名患者被诊断为 CD/FND,平均年龄 42.4,标准差 (SD)  = 13.8 岁,79.3% 为女性,289 名患者患有其他 SSRD(平均年龄 42.1,SD = 13.3,60.2% 是女性)。患者完成了一项神经心理学测试,该测试涉及广泛的神经认知领域,包括信息处理速度、注意力和执行功能。根据规范性数据比较,CD/FND 患者在所有神经认知领域都存在具有临床意义的神经认知缺陷。CD/FND 患者在信息处理速度(数字符号替换测试 ( V  = .115, p  = .035)、Stroop Color-Word Test (SCWT) 卡 1 ( V  = .190 ) 方面的表现也明显差于其他 SSRD 患者, p  = .006) 和 SCWT 卡 2 ( V  = .244, p < .001)。在其他神经认知域中没有观察到 CD/FND 与其他 SSRD 的差异。这些发现表明,与其他 SSRD 患者相比,CD/FND 患者在信息处理速度测试中的表现更差。
更新日期:2020-03-29
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