A copper‐catalyzed addition of alkynes to phthalazin‐2‐ium bromide has been developed under mild conditions, leading to the production of propargylamines analogues. The addition products of a broad scope of phthalazin‐2‐ium bromides bearing various N ‐benzyl or alkyl can be obtained in good to high yields. Moderate enantioselectivity was observed in preliminary screening studies of chiral organic ligand.

中文翻译：

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铜催化向酞菁2溴化溴化物中添加末端炔烃

在温和的条件下开发了铜催化的炔烃向酞菁-2-溴化铵的加成反应，从而生产了炔丙基胺类似物。可以以良好或高收率获得各种含各种N-苄基或烷基的酞菁-2-溴化溴化物的加成产物。在手性有机配体的初步筛选研究中观察到中等的对映选择性。