Worldwide industrial development has released hazardous polycyclic aromatic compounds into the environment. These pollutants need to be removed to improve the quality of the environment. Chemotaxis mechanism has increased the bioavailability of these hydrophobic compounds to microorganisms. The mechanism, however, is poorly understood at the ligand and chemoreceptor interface. Literature is unable to furnish a compiled review of already published data on up-to-date research on molecular aspects of chemotaxis mechanism, ligand and receptor-binding mechanism, and downstream signaling machinery. Moreover, chemotaxis-linked biodegradation of aromatic compounds is required to understand the chemotaxis role in biodegradation better. To fill this knowledge gap, the current review is an attempt to cover PAHs occurrence, chemical composition, and potential posed risks to humankind. The review will cover the aspects of microbial signaling mechanism, the structural diversity of methyl-accepting chemotaxis proteins at the molecular level, discuss chemotaxis mechanism role in biodegradation of aromatic compounds in model bacterial genera, and finally conclude with the potential of bacterial chemotaxis for aromatics biodegradation.

全球工业发展已将有害的多环芳族化合物释放到环境中。需要去除这些污染物以改善环境质量。趋化机理增加了这些疏水性化合物对微生物的生物利用度。然而，在配体和化学感受器界面处的机理了解甚少。文献无法提供有关趋化性机制，配体和受体结合机制以及下游信号传导机制的分子方面的最新研究的已发表数据的汇编综述。此外，需要芳香族化合物的趋化性相关的生物降解作用，以更好地了解趋化性在生物降解中的作用。为了填补这一知识空白，本次审查旨在涵盖PAH的发生，化学成分，以及潜在的危害人类。综述将涵盖微生物信号传导机制，在分子水平上甲基化趋化性蛋白的结构多样性，探讨趋化性机理在模型细菌属中对芳香族化合物生物降解的作用，最后总结细菌趋化性对芳香族化合物的潜力。生物降解。