Improving the content and production of high-value ketocarotenoid pigments is critical for the commercialization of microalgal biorefineries. This study reported the use of magnesium aminoclay (MgAC) nanoparticles for enhancement of astaxanthin production by Haematococcus pluvialis in photoautotrophic cultures. Addition of 1.0 g/L MgAC significantly promoted cellular astaxanthin biosynthesis (302±69 pg/cell), presumably by inducing tolerable oxidative stress, corresponding to a 13.7-fold higher production compared to that in the MgAC-untreated control (22±2 pg/cell). The lipid content and cell size of H. pluvialis improved by 13.6- and 2.1-fold, respectively, compared to that of the control. Despite reduced cell numbers, the overall astaxanthin production (10.3±0.4 mg/L) improved by 40% compared to the control (7.3±0.6 mg/L), owing to improved biomass production. However, an MgAC dosage above 1.0 g/L inhibited biomass production by inducing electrostatic cell wall destabilization and aggregation. Therefore, MgAC-induced stimulation of algae varies widely based on their morphological and physiological characteristics.

提高微缩酮类胡萝卜素颜料的含量和生产对于微藻生物精炼厂的商业化至关重要。该研究报告的增强虾青素生产的采用了镁aminoclay（MgAC）纳米粒子由雨生红球在光自养培养。添加1.0 g / L MgAC可以显着促进细胞虾青素的生物合成（302±69 pg /细胞），推测是通过诱导可耐受的氧化应激，与未经MgAC处理的对照（22±2 pg）相比，产量提高了13.7倍/细胞）。脂质含量和细胞大小的H.生红球藻与对照组相比，分别提高了13.6倍和2.1倍。尽管细胞数量减少，但由于改善了生物量的产生，虾青素的总产量（10.3±0.4 mg / L）比对照（7.3±0.6 mg / L）提高了40％。但是，高于1.0 g / L的MgAC剂量会引起静电细胞壁失稳和聚集，从而抑制生物量的产生。因此，基于MgAC诱导的藻类的形态和生理特性差异很大。