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Fluorescent detection of loop diuretics by sensors based on zinc(II) bis(dipyrromethenate)s
Dyes and Pigments ( IF 4.5 ) Pub Date : 2020-03-30 , DOI: 10.1016/j.dyepig.2020.108389
Alexander A. Ksenofontov , Mikhail M. Lukanov , Elena V. Antina

This paper is a follow-up to our recent study of the zinc(II) bis(dipyrromethenate)s ([Zn2L2]s) sensory capabilities for furosemide detection. We complement our studies with the results of torasemide fluorescent detection by [Zn2L2]s with 0.037–0.11 μg mL−1 detection limit in organic media. The fluorescent sensory materials based on ethyl cellulose doped with [Zn2(1)2] have been developed. It has been shown that ones have high sensitivity to the loop diuretics presence (in 1-propanol the furosemide detection limit is 24 μg mL−1, while torasemide detection limit is 43 μg mL−1). The sensory materials were successfully used for loop diuretics detecting in human urine samples. The results show the loop diuretics detection using [Zn2L2]s and fluorescent sensory materials based on them to be a simple and highly sensitive method of ones detection in organic media and human urine.



中文翻译:

锌(II)双(双嘧啶)锌盐传感器对detection利尿剂的荧光检测

本文是对我们最近对呋塞米检测中的双(dipyrromethenate)锌([Zn 2 L 2 ] s)感官能力研究的后续研究。我们通过[锌与托拉塞米荧光检测的结果补充我们的研究2大号2 ] S与0.037-0.11  μ克毫升-1在有机介质中的检测限。已经开发了基于掺杂有[Zn 212 ]的乙基纤维素的荧光感官材料。已表明对环利尿剂的存在具有很高的敏感性(在1-丙醇中,速尿的检出限为 24μg mL -1,而托拉塞米检出限为43  μ克毫升-1)。感官材料已成功用于人类尿液样品中loop利尿剂的检测。结果表明,使用[Zn 2 L 2 ] s和基于它们的荧光传感材料检测the利尿剂是一种简单且高度灵敏的有机介质和人类尿液中尿ones子检测方法。

更新日期:2020-03-30
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