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Nervous system involvement after infection with COVID-19 and other coronaviruses
Brain, Behavior, and Immunity ( IF 15.1 ) Pub Date : 2020-07-01 , DOI: 10.1016/j.bbi.2020.03.031
Yeshun Wu 1 , Xiaolin Xu 2 , Zijun Chen 3 , Jiahao Duan 3 , Kenji Hashimoto 4 , Ling Yang 3 , Cunming Liu 5 , Chun Yang 5
Affiliation  

Abstract Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit neurotropic properties and may also cause neurological diseases. It is reported that CoV can be found in the brain or cerebrospinal fluid. The pathobiology of these neuroinvasive viruses is still incompletely known, and it is therefore important to explore the impact of CoV infections on the nervous system. Here, we review the research into neurological complications in CoV infections and the possible mechanisms of damage to the nervous system.

中文翻译:

感染 COVID-19 和其他冠状病毒后神经系统受累

摘要 病毒感染对神经功能有不利影响,甚至会造成严重的神经损伤。最近,冠状病毒 (CoV),尤其是严重急性呼吸系统综合症 CoV 2 (SARS-CoV-2),表现出嗜神经特性,也可能导致神经系统疾病。据报道,冠状病毒可以在大脑或脑脊液中发现。这些神经侵袭性病毒的病理生物学仍不完全清楚,因此探索 CoV 感染对神经系统的影响非常重要。在这里,我们回顾了对 CoV 感染神经系统并发症的研究以及神经系统损伤的可能机制。
更新日期:2020-07-01
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