Hip fractures constitute a major health problem in elderly people and are often fall-related. Several factors can contribute to a fall episode leading to hip fracture, including fall-risk-increasing drugs (FRIDs), which are often used by elderly people. We aimed to investigate the prevalence of medication-related falls and to assess the role of FRIDs and potentially inappropriate medications (PIMs) in a population of elderly patients hospitalized for a hip fracture. We reviewed the patient records of 200 consecutive patients, aged ≥65 years, who were admitted for a hip fracture and evaluated whether medications were likely to have contributed to the fall episode. PIMs were identified using the Screening Tool of Older Persons’ Prescriptions version 2 (STOPP) and by evaluating indications, contra-indications and interactions of the prescribed medications for each patient. FRIDs were used by 175 patients (87.5%). Medications were considered a likely contributor to the fall in 82 patients (41%). These were most often psychotropic medications alone or in combination with antihypertensives and/or diuretics. The 82 patients with suspected medication-related falls used more medications, FRIDs and PIMs than the rest of the patients, and in 74 (90%) of the 82 patients, at least one medication considered to be a contributor to the fall was also a PIM. The prevalence of suspected medication-related falls was 41%. It seems likely that a medication review could have reduced, though not eliminated, the risk of falling in this group of patients.

中文翻译：

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连续200名老年髋部骨折患者中与药物相关的跌倒患病率：一项横断面研究

髋部骨折是老年人的主要健康问题，通常与摔倒有关。导致髋部骨折的跌倒发作有多种因素，包括增加跌倒风险的药物（FRIDs），这是老年人经常使用的药物。我们的目的是调查与药物相关的跌倒的患病率，并评估FRID和可能不适当的药物（PIM）在因髋部骨折住院的老年患者人群中的作用。我们回顾了连续200例年龄≥65岁的因髋部骨折而入院的患者病历，并评估了药物是否可能导致了秋季发作。使用“老年人处方筛查工具第2版”（STOPP）并通过评估适应症来识别PIM，每个患者的禁忌症和处方药的相互作用。FRIDs用于175例患者（占87.5％）。认为药物可能是导致82例患者下降的原因（41％）。这些通常是单独使用精神药物或与降压药和/或利尿药合用。怀疑与药物相关的跌倒的82例患者比其余患者使用了更多的药物，FRID和PIM，在82例患者中的74例（90％）中，至少一种被认为是导致跌倒的药物也是PIM。怀疑与药物相关的跌倒患病率为41％。药物审查似乎可以减少（但不能消除）该组患者的跌倒风险。认为药物可能是导致82例患者下降的原因（41％）。这些通常是单独使用精神药物或与降压药和/或利尿药合用。怀疑与药物相关的跌倒的82例患者比其余患者使用了更多的药物，FRID和PIM，在82例患者中的74例（90％）中，至少一种被认为是导致跌倒的药物也是PIM。怀疑与药物相关的跌倒患病率为41％。药物审查似乎可以减少（但不能消除）该组患者的跌倒风险。认为药物可能是导致82例患者下降的原因（41％）。这些通常是单独使用精神药物或与降压药和/或利尿药合用。怀疑与药物相关的跌倒的82例患者比其余患者使用了更多的药物，FRID和PIM，在82例患者中的74例（90％）中，至少一种被认为是导致跌倒的药物也是PIM。怀疑与药物相关的跌倒患病率为41％。药物审查似乎可以减少（但不能消除）该组患者的跌倒风险。怀疑与药物相关的跌倒的82例患者比其余患者使用了更多的药物，FRID和PIM，并且在82例患者中的74例（90％）中，至少一种被认为是导致跌倒的药物也是PIM。怀疑与药物相关的跌倒患病率为41％。药物审查似乎可以减少（但不能消除）该组患者的跌倒风险。怀疑与药物相关的跌倒的82例患者比其余患者使用了更多的药物，FRID和PIM，在82例患者中的74例（90％）中，至少一种被认为是导致跌倒的药物也是PIM。怀疑与药物相关的跌倒患病率为41％。药物审查似乎可以减少（但不能消除）该组患者的跌倒风险。