The level of automation in mechanical ventilation has been steadily increasing over the last few decades. There has recently been renewed interest in physiological closed-loop control of ventilation. The development of these systems has followed a similar path to that of manual clinical ventilation, starting with ensuring optimal gas exchange and shifting to the prevention of ventilator-induced lung injury. Systems currently aim to encompass both aspects, and early commercial systems are appearing. These developments remain unknown to many clinicians and, hence, limit their adoption into the clinical environment. This review shows the evolution of the physiological closed-loop control of mechanical ventilation.

中文翻译：

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生理闭环通气的曙光——综述

在过去的几十年里，机械通风的自动化水平一直在稳步提高。最近，人们对通气的生理闭环控制重新产生了兴趣。这些系统的开发遵循与手动临床通气类似的路径，从确保最佳气体交换开始，然后转向预防呼吸机引起的肺损伤。目前的系统旨在涵盖这两个方面，并且正在出现早期的商业系统。许多临床医生仍然不知道这些发展，因此限制了它们在临床环境中的采用。这篇综述展示了机械通气的生理闭环控制的演变。