Epothilone is a kind of macrolide compound, which has anticancer activity and strong inhibitory effect on breast cancer and rectal cancer cells. Herein, the chemical and biological synthesis of epothilones and how to improve fermentation yield and separation methods were summarized and discussed.

中文翻译：

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具有抗癌活性的埃坡霉素的制备和分离。

埃坡霉素是一种大环内酯类化合物，对乳腺癌和直肠癌细胞具有抗癌活性和较强的抑制作用。本文总结并讨论了埃坡霉素的化学和生物合成以及如何提高发酵产量和分离方法。