A dual beam optical coherence tomography (OCT) instrument has been developed for flow measurement that offers advantages over microscope derived imaging techniques. It requires only a single optical access port, allows simultaneous imaging of the microfluidic channel, does not require fluorescent seed particles, and can provide a millimetre-deep depth-section velocity profile (as opposed to horizontal-section). The dual beam instrument performs rapid re-sampling of particle positions, allowing measurement of faster flows. In this paper, we develop the methods and processes necessary to make 2D quantitative measurements of the flow-velocity using dual beam OCT and present exemplar results in a microfluidic chip. A 2D reference measurement of the Poiseuille flow in a microfluidic channel is presented over a spanwise depth range of 700 m and streamwise length of 1600 m with a spatial resolution of 10 m , at velocities up to 50 m m / s . A measurement of a more complex flow field is also demonstrated in a sloped microfluidic section.

中文翻译：

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使用双束OCT的2D空间分辨深度截面微流体流速仪。

已开发出一种用于流量测量的双光束光学相干断层扫描（OCT）仪器，它比显微镜衍生的成像技术更具优势。它仅需要一个光学访问端口，就可以同时对微流体通道进行成像，不需要荧光种子颗粒，并且可以提供毫米深的深度截面速度曲线（与水平截面相对）。双束仪器对颗粒位置进行快速重新采样，从而可以测量更快的流量。在本文中，我们开发了使用双束OCT对流速进行2D定量测量所需的方法和过程，并在微流控芯片中显示了示例结果。在700 m的跨展深度范围和1600 m的沿流长度的空间分辨率为10 m的速度高达50 mm / s的情况下，提出了微流道中Poiseuille流动的二维参考测量。在倾斜的微流体截面中也显示了对更复杂流场的测量。