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Anti-adhesion activity of phytochemicals to prevent Campylobacter jejuni biofilm formation on abiotic surfaces
Phytochemistry Reviews ( IF 7.7 ) Pub Date : 2020-03-26 , DOI: 10.1007/s11101-020-09669-6
Anja Klančnik , Katarina Šimunović , Meta Sterniša , Dina Ramić , Sonja Smole Možina , Franz Bucar

Biofilms provide a protective environment for pathogens such as Campylobacter jejuni, the most prevalent foodborne pathogen, and biofilm formation can enhance bacterial survival in hostile environments. Adhesion of bacteria to the different materials of industrial surfaces is the first step in biofilm formation. Modulation of bacterial adhesion and biofilm formation thus represent important targets in alternative control strategies for reduction of pathogens in food-processing environments. With the high prevalence of C. jejuni and the lack of effective control measures, new control strategies are needed to block adhesion and biofilm formation on food contact surfaces in the food industry, with a focus here on natural antimicrobial phytochemicals. Plants remain a poorly recognized yet vast source of such antimicrobials. Valuable phytochemicals can be obtained directly from plant materials but also from agro-food by-products and waste materials. These materials represent a source of important plant bioactive phytochemicals that are effective for prevention of bacterial adhesion. In this review, we will focus on the anti-adhesion activities of phytochemicals targeted against C. jejuni, on the appropriate methodologies to determine anti-adhesion effects of phytochemicals, on the mechanisms of C. jejuni adhesion, and thus possible targets for reduction and control of this foodborne pathogen in food processing environments.



中文翻译:

植物化学物质的抗粘附活性可防止空肠弯曲菌在非生物表面形成生物膜

生物膜为诸如空肠弯曲菌Campylobacter jejuni)等病原体提供了保护性环境,空肠弯曲菌是最普遍的食源性病原体,生物膜的形成可以增强细菌在恶劣环境中的存活率。细菌对工业表面不同材料的粘附是生物膜形成的第一步。因此,细菌粘附和生物膜形成的调节代表了在食品加工环境中减少病原体的替代控制策略中的重要目标。空肠弯曲菌的流行率很高由于缺乏有效的控制措施,因此需要新的控制策略来阻止食品工业中食品接触表面上的粘附和生物膜形成,重点是天然抗菌植物化学物质。植物仍然是这类抗菌素的公认来源不多,但来源广泛。有价值的植物化学物质可以直接从植物原料中获得,也可以从农业食品副产品和废料中获得。这些材料代表了有效预防细菌粘附的重要植物生物活性植物化学物质的来源。在这篇综述中,我们将着重于针对空肠弯曲杆菌的植物化学物质的抗黏附活性,确定对空肠弯曲菌的植物的抗黏附作用的适当方法论 粘附性,因此是在食品加工环境中减少和控制这种食源性病原体的可能目标。

更新日期:2020-04-22
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