Dysmenorrhea is one of the most common menstrual disorders and is influenced by various factors. Psychological disorders including anxiety, depression, and stress have been suggested as influencing dysmenorrhea, but previous findings are inconsistent. This study will investigate the relationship between depression/anxiety/stress and dysmenorrhea using a systematic review and meta-analysis. Online databases including PsycINFO, Scopus, PubMed, Science Direct, ProQuest, ISI Web of Knowledge, and Embase will be searched. Appropriate keywords and MeSH terms will be used to retrieve the journal papers published from 1990 until the end of December 2019. To improve search coverage, the reference lists of all included studies will be reviewed to find eligible papers. Inclusion criteria include the following: descriptive, cohort, case-control, and cross-sectional studies; the relationship between depression/anxiety/stress and dysmenorrhea being an objective of the study; and published in peer-reviewed journals. The paper selection, data extraction, and quality assessment of selected studies will be performed independently by two researchers, and disagreements will be resolved through discussions. The Newcastle-Ottawa Quality Assessment Scale will be used to assess the quality of selected studies. A quantitative synthesis will be performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) via the STATA software, if retrieving enough number of studies with no severe methodological heterogeneities. Otherwise, qualitative synthesis will be used to report the findings. To the best of our knowledge, this will be the first systematic review on this topic. Performing an inclusive search in major databases over a wide timescale is one key strength of the proposed study and will maximize the coverage of the original research studies on this topic. Results of present study are expected to lead to deeper understanding the relationship between common mental health conditions and dysmenorrhea. PROSPERO CRD42018102199

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抑郁、焦虑、压力和痛经：系统评价方案

痛经是最常见的月经失调之一，受多种因素影响。包括焦虑、抑郁和压力在内的心理障碍被认为会影响痛经，但之前的研究结果并不一致。本研究将通过系统评价和荟萃分析来探讨抑郁/焦虑/压力与痛经之间的关系。将检索包括 PsycINFO、Scopus、PubMed、Science Direct、ProQuest、ISI Web of Knowledge 和 Embase 在内的在线数据库。将使用适当的关键词和 MeSH 术语来检索从 1990 年到 2019 年 12 月底发表的期刊论文。为了提高搜索覆盖率，将审查所有纳入研究的参考文献列表以查找符合条件的论文。纳入标准包括以下内容：描述性研究、队列研究、病例对照研究和横断面研究；抑郁/焦虑/压力与痛经之间的关系是该研究的一个目标；并发表在同行评审期刊上。所选研究的论文选择、数据提取和质量评估将由两名研究人员独立进行，分歧将通过讨论解决。纽卡斯尔-渥太华质量评估量表将用于评估所选研究的质量。如果检索到足够数量且没有严重方法学异质性的研究，将通过 STATA 软件使用系统评价和荟萃分析的首选报告项目 (PRISMA) 进行定量综合。否则，将使用定性综合来报告结果。据我们所知，这将是关于该主题的第一次系统综述。在广泛的时间范围内对主要数据库进行包容性搜索是拟议研究的一个关键优势，并将最大限度地扩大有关该主题的原始研究的覆盖范围。本研究的结果预计将有助于更深入地了解常见心理健康状况与痛经之间的关系。普洛斯彼罗 CRD42018102199