In recent years, the self-assembly of copolymer micelles has become an appealing frontier of supramolecular chemistry as a strategy to construct superstructures with multiple levels of complexity. The assembly of copolymer micelles is a form of higher-level self-assembly occurring at the nanoscale level where the building blocks are preassembled micelles. Compared to one-step hierarchical self-assembly, this assembly strategy is superior for manipulating multilevel architectures because the structures of the building blocks and higher-order hierarchies can be regulated separately in the first and higher-level assembly, respectively. However, despite the substantial advances in the self-assembly of copolymer micelles in recent years, universal laws have not been comprehensively summarized. This review article aims to provide an overview of the current progress and developing prospects of the self-assembly of copolymer micelles. In particular, the significant role of theoretical simulations in revealing the mechanism of copolymer micelle self-assembly is discussed.

中文翻译：

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共聚物胶束的自组装：用于构建层次结构的高级组装。

近年来，共聚物胶束的自组装已成为超分子化学作为构建具有多个复杂程度的超结构的策略的引人注目的前沿。共聚物胶束的组装是在纳米级发生的高级自组装形式，其中构件是预组装的胶束。与一步式分层自组装相比，此组装策略在操纵多层体系结构方面更为出色，因为可以分别在第一层组装和高层组装中分别调节构建基块的结构和更高层次的层次结构。然而，尽管近年来在共聚物胶束的自组装方面取得了实质性进展，但尚未全面总结普遍定律。这篇综述文章旨在概述共聚物胶束自组装的当前进展和发展前景。特别是，讨论了理论模拟在揭示共聚物胶束自组装机理中的重要作用。