We have developed a model for evaluating the integral intercellular interactions in the “endotheliocyte‐neutrophil” system and have shown the high variability of adhesion contacts in different donors associated with different expression profiles of neutrophils. Two methods (forсe spectroscopy‐spectroscopy and scanning ion‐conductance microscopy) showed a decrease in the rigidity of the membrane‐cytoskeletal complex of neutrophils under the influence of Staphylococcus aureus 2879 M. Adding this strain to the “endotheliocyte‐neutrophil” system caused a statistically significant decrease in the adhesion force and adhesion work, which indicates a change in the expression profile and physicochemical properties of membranes of both types of interacting cells (neutrophils and endotheliocytes).

中文翻译：

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金黄色葡萄球菌调节嗜中性粒细胞和内皮细胞之间的粘附接触。

我们开发了一个模型，用于评估“内皮细胞-中性粒细胞”系统中完整的细胞间相互作用，并显示出与中性粒细胞不同表达谱相关的不同供体中粘附接触的高度可变性。两种方法（强制光谱 - 光谱和扫描离子电导显微镜）显示在金黄色葡萄球菌2879 M的影响下中性粒细胞的膜 - 细胞骨架复合体的刚度降低。将这种菌株添加到“内皮细胞 - 中性粒细胞”系统中导致粘附力和粘附功在统计学上显着降低，这表明两种相互作用的细胞（中性粒细胞和内皮细胞）的细胞膜的表达谱和理化特性发生了变化。