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Oxyanion transport across lipid bilayers: direct measurements in large and giant unilamellar vesicles.
Chemical Communications ( IF 4.9 ) Pub Date : 2020-04-02 , DOI: 10.1039/c9cc09888g
Krzysztof M Bąk 1 , Bartjan van Kolck 2 , Krystyna Maslowska-Jarzyna 1 , Panagiota Papadopoulou 2 , Alexander Kros 2 , Michał J Chmielewski 1
Affiliation  

A simple di(thioamido)carbazole 1 serves as a potent multispecific transporter for various biologically relevant oxyanions, such as drugs, metabolites and model organic phosphate. The transport kinetics of a wide range of oxyanions can be easily quantified by a modified lucigenin assay in both large and giant unilamellar vesicles.

中文翻译:

氧阴离子跨脂质双层的运输:大型和巨型单层囊泡的直接测量。

简单的二(硫代氨基)咔唑 1 可作为多种生物相关含氧阴离子(例如药物、代谢物和模型有机磷酸盐)的有效多特异性转运蛋白。通过改进的光泽精测定,可以轻松地量化大范围和巨型单层囊泡中各种氧阴离子的转运动力学。
更新日期:2020-03-25
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