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Effect of supra-nutritional selenium-enriched probiotics on hematobiochemical, hormonal, and Doppler hemodynamic changes in male goats.
Environmental Science and Pollution Research ( IF 5.8 ) Pub Date : 2020-03-25 , DOI: 10.1007/s11356-020-08294-2
Ahmed S Mandour 1, 2 , Haney Samir 3, 4 , Marwa A El-Beltagy 5 , Mohamed M Abdel-Daim 6, 7 , Watanabe Izumi 8 , Danfu Ma 2 , Katsuhiro Matsuura 2 , Ryou Tanaka 2 , Gen Watanabe 4
Affiliation  

In this study, the influence of supra-nutritional organic selenium (Se) supplement on hematology and plasma biochemicals, including antioxidant parameters and plasma reproductive hormones, as well as blood flow characteristics in the supratesticular and common carotid arteries (STA and CCA, respectively) were investigated. For this purpose, 15 male goats were used and classified into three equal groups according to the supplementation of the basal diet (BD): negative control (NC), probiotic (Pro), and Se-probiotic (Se-Pro) groups. Blood perfusion in the STA and CCA was assessed by Doppler ultrasonography at three different time intervals: at the experimental onset (T0), 3 weeks of dietary supplement (T3), and after 6 weeks of observation (T6). Concomitantly, blood samples were withdrawn for hematobiochemical and hormonal changes. Results revealed no evidence of clinical abnormality, with some enhanced hematological parameters and antioxidant (SOD and GPX) levels in goats of the Se-Pro and Pro groups. High concentrations of FSH were found in the Se-Pro at T6 compared to its values in other groups. Similarly, testosterone levels were elevated in the Pro and Se-Pro groups at T3 compared to other time points. There were significant increases in levels of IGF-1 in the Pro and Se-Pro groups compared to the NC group. Significant (P < 0.05) increases in the values of the blood volume within the CCA and the STA were noted in the Se-Pro group, and the highest values were observed at T6 (CCA, 427.4 ± 33 ml/min; STA, 49.9 ± 5.0 ml/min). In conclusion, supra-nutritional organic selenium improves some hematobiochemical parameters, reproductive hormones, and the blood perfusion within the CCA and STA in goats.



中文翻译:

超营养富硒益生菌对雄性山羊血液生化,激素和多普勒血流动力学变化的影响。

在这项研究中,超营养有机硒(Se)补充剂对血液学和血浆生化试剂的影响,包括抗氧化剂参数和血浆生殖激素,以及上,上颈动脉(分别为STA和CCA)的血流特性被调查了。为此,使用了15只公山羊,并根据基础饮食(BD)的补充分为三个相等的组:阴性对照组(NC),益生菌(Pro)和硒益生菌(Se-Pro)组。通过多普勒超声检查在三个不同的时间间隔对STA和CCA中的血液灌注进行评估:在实验发作(T0),饮食补充3周(T3)和观察6周后(T6)。同时,抽取血样进行血液生化和激素变化。结果表明,没有发现临床异常的迹象,Se-Pro和Pro组山羊的血液学参数和抗氧化剂(SOD和GPX)水平有所提高。与其他组相比,Se-Pro在T6时发现了高浓度的FSH。同样,与其他时间点相比,Pro和Se-Pro组在T3时睾丸激素水平升高。与NC组相比,Pro和Se-Pro组的IGF-1水平显着增加。重大 (与其他时间点相比,Pro和Se-Pro组在T3时睾丸激素水平升高。与NC组相比,Pro和Se-Pro组的IGF-1水平显着增加。重大 (与其他时间点相比,Pro和Se-Pro组在T3时睾丸激素水平升高。与NC组相比,Pro和Se-Pro组的IGF-1水平显着增加。重大 ( 在Se-Pro组中,CCA和STA中的血容量值增加(P <0.05),并且在T6时观察到最高值(CCA,427.4±33 ml / min; STA,49.9±5.0毫升/分钟)。总之,超营养有机硒改善了山羊的CCA和STA中的某些血液生化指标,生殖激素和血液灌注。

更新日期:2020-03-25
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