Vaccinia virus (VACV), the prototype orthopoxvirus, is the first live viral vaccine used to protect against smallpox, one of the most feared infectious diseases of humans (1). This outstanding achievement was possible because even as the various orthopoxviruses evolved and diversified they often retained major parts of their virion composition...

中文翻译：

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修饰的痘苗病毒安卡拉在人体细胞中复制的重要基因[微生物学]

痘苗病毒（VACV），正痘病毒的原型，是第一种用于预防天花的活病毒疫苗，天花是人类最担心的传染病之一（1）。取得这一杰出成就是可能的，因为即使各种正痘病毒不断发展和多样化，它们也经常保留其病毒体组成的主要部分。