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DNA origami protection and molecular interfacing through engineered sequence-defined peptoids [Applied Biological Sciences]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-03-24
Shih-Ting Wang, Melissa A. Gray, Sunting Xuan, Yiyang Lin, James Byrnes, Andy I. Nguyen, Nevena Todorova, Molly M. Stevens, Carolyn R. Bertozzi, Ronald N. Zuckermann, Oleg Gang

DNA nanotechnology has established approaches for designing programmable and precisely controlled nanoscale architectures through specific Watson−Crick base-pairing, molecular plasticity, and intermolecular connectivity. In particular, superior control over DNA origami structures could be beneficial for biomedical applications, including biosensing, in vivo imaging, and drug and gene delivery. However, protecting DNA origami...

中文翻译:

DNA折纸的保护和通过工程化序列定义的类肽进行的分子连接[应用生物科学]

DNA纳米技术已经建立了通过特定的Watson-Crick碱基配对,分子可塑性和分子间连接性来设计可编程和精确控制的纳米级体系结构的方法。特别是,对DNA折纸结构的更好控制可能有益于生物医学应用,包括生物传感,体内成像以及药物和基因的传递。但是,保护DNA折纸...
更新日期:2020-03-26
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