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CD300f immunoreceptor is associated with major depressive disorder and decreased microglial metabolic fitness [Immunology and Inflammation]
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.580 ) Pub Date : 2020-03-24
Natalia Lago, Fernanda N. Kaufmann, Maria Luciana Negro–Demontel, Daniela Ali–Ruiz, Gabriele Ghisleni, Natalia Rego, Andrea Arcas–Garcia, Nathalia Vitureira, Karen Jansen, Luciano M. Souza, Ricardo A. Silva, Diogo R. Lara, Bruno Pannunzio, Juan Andres Abin–Carriquiry, Jesus Amo–Aparicio, Celia Martin–Otal, Hugo Naya, Dorian B. McGavern, Joan Sayos, Ruben Lopez–Vales, Manuella P. Kaster, Hugo Peluffo

A role for microglia in neuropsychiatric diseases, including major depressive disorder (MDD), has been postulated. Regulation of microglial phenotype by immune receptors has become a central topic in many neurological conditions. We explored preclinical and clinical evidence for the role of the CD300f immune receptor in the fine regulation of...
更新日期:2020-03-26

 

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