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Reactivity of Salivary Uric Acid in Response To Social Evaluative Stress in African Americans
Biological Psychology ( IF 2.6 ) Pub Date : 2020-05-01 , DOI: 10.1016/j.biopsycho.2020.107882
Todd Lucas 1 , Jenna L Riis 2 , Zachary Buchalski 3 , Caroline E Drolet 3 , Anurag Dawadi 3 , Douglas A Granger 4
Affiliation  

High uric acid (UA) is associated with hypertension and cardiovascular disease (CVD), both of which occur disproportionately among African Americans. High UA also predicts greater blood pressure reactivity responses to acute social stress. However, whether UA itself shows reactivity in response to stress is unknown. We evaluated salivary uric acid (sUA) and blood pressure reactivity in response to acute social stress. Healthy African Americans (N = 103; 32% male; M age = 31.36 years), completed the Trier Social Stress Test. sUA and blood pressure measurements were taken before, during and after the stressor task. sUA showed significant reactivity and recovery, especially among older African Americans. Total sUA activation was also associated with systolic and diastolic blood pressure total activation. Findings illuminate that acute stress may be a way in which UA is implicated in hypertension and CVD, suggesting a critical need to explore UA reactivity as a novel parameter of the acute stress response.

中文翻译:

唾液尿酸对非裔美国人社会评价压力的反应

高尿酸 (UA) 与高血压和心血管疾病 (CVD) 相关,这两种疾病在非裔美国人中的发生率不成比例。高 UA 还预示着对急性社会压力会有更大的血压反应性反应。然而,UA 本身是否表现出对压力的反应尚不清楚。我们评估了唾液尿酸 (sUA) 和血压反应性以应对急性社会压力。健康的非裔美国人(N = 103;32% 男性;M 年龄 = 31.36 岁),完成了特里尔社会压力测试。在压力源任务之前、期间和之后进行 sUA 和血压测量。sUA 表现出显着的反应性和恢复性,尤其是在老年非洲裔美国人中。总 sUA 激活也与收缩压和舒张压总激活有关。
更新日期:2020-05-01
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