当前位置: X-MOL 学术Sci. Total Environ. › 论文详情
The relevance of particle size distribution and bioaccessibility on human health risk assessment for trace elements measured in indoor dust
Science of the Total Environment ( IF 5.589 ) Pub Date : 2020-03-25 , DOI: 10.1016/j.scitotenv.2020.137931
Israel N.Y. Doyi; Vladimir Strezov; Cynthia F. Isley; Tahereh Yazdanparast; Mark Patrick Taylor

Trace metal contaminants in indoor dust pose a significant potential exposure risk to people because of the time spent indoors and the readily ingested and inhaled fine-grained composition of indoor dusts. However, there is limited trace metal data available on the specific interaction of dust particle size fraction and their respective bioaccessibility/bioavailability and its consequent effect on health risk assessment. This study addresses this knowledge gap by examining bioaccessible and bioavailable trace element concentrations (As, Cr, Cu, Mn, Ni, Pb, Zn) in 152 discrete size fractions from 38 indoor vacuum samples from part of larger dataset (n = 376) of indoor dust from Sydney, Australia. Arsenic, Cu, Ni, Pb and Zn were most concentrated in the 90–150 μm fraction with Cr and Mn being more concentrated in <45 μm fraction. Dust particle size fractions <45 μm, 45–90 μm, 90–150 μm and 150–250 μm were analysed for their individual gastric phase (G-alone) in vitro trace element bioaccessibilities, with Pb exposure risk estimated using the United States Environmental Protection Agency's Integrated Exposure Uptake Biokinetic (IEUBK) children's model. Mean Pb bioaccessibility was 59.6%, 42%, 62% and 62.2% for <45 μm, 45–90 μm, 90–150 μm, and 150–250 μm, respectively. Mean Pb absolute bioavailability (ABA) was lower at 26.2%, 18.4%, 27.2% and 27.3% for size fractions <45 μm, 45–90 μm, 90–150 μm, and 150–250 μm, respectively. The predicted blood Pb (PbB) levels for a hypothetical child aged 1 to 3 years for each of these the dust particle size fractions was >5 μg/dL. Lead concentrations measured in the selected dust samples show a potential for adverse health impacts from contaminant exposure on young children with the greatest risk being from indoor dust sized 90–150 μm.
更新日期:2020-03-26

 

全部期刊列表>>
聚焦肿瘤,探索癌症
欢迎探索2019年最具下载量的材料科学论文
宅家赢大奖
向世界展示您的会议墙报和演示文稿
全球疫情及响应:BMC Medicine专题征稿
新版X-MOL期刊搜索和高级搜索功能介绍
化学材料学全球高引用
ACS材料视界
x-mol收录
自然科研论文编辑服务
南方科技大学
南方科技大学
舒伟
中国科学院长春应化所于聪-4-8
复旦大学
课题组网站
X-MOL
香港大学化学系刘俊治
中山大学化学工程与技术学院
试剂库存
天合科研
down
wechat
bug