The covalent grafting of poly (sodium 4- styrene sulfonate) on poly (ɛ-caprolactone) was proved to enhance the bioactivity of this polymer. The aim of this article was to perform kinetic studies of the activation and grafting processes and illustrate the influence of several parameters on the grafting rate and on the degradation of the polymer substrate. Results showed that the active groups created on poly (ɛ-caprolactone) surface by ozonation reach a maximum concentration after a short exposure time. Moreover, a kinetic study of poly (sodium 4- styrene sulfonate) grafting on poly (ɛ-caprolactone) substrate showed that the activation energy of this process was low and the influence of conditions such as pH, monomer concentration, time reaction and grafting temperature was deeply significant for the outcome of the treatment. Besides, ozone oxidation and thermal grafting lead to surface degradation, under certain conditions, for example in the presence of Mohr's salt used as a catalyst to enhance grafting rate. The whole study illustrates that ozone-induced grafting is a strong instrument for surface functionalization, although its parameters should be wisely studied and carefully selected. Poly (sodium 4- styrene sulfonate) functionalization improves bioactivity of poly (ɛ-caprolactone) while decreasing the slowness of its biodegradation.

事实证明，聚（4-苯乙烯磺酸钠）在聚（ε-己内酯）上的共价接枝可以提高该聚合物的生物活性。本文的目的是对活化和接枝过程进行动力学研究，并说明几个参数对接枝率和聚合物基质降解的影响。结果表明，通过臭氧化作用在聚（ε-己内酯）表面形成的活性基团在短时间暴露后达到最大浓度。此外，在聚（ε-己内酯）底物上进行聚（4-苯乙烯磺酸钠）接枝的动力学研究表明，该方法的活化能低，并且受到pH，单体浓度，时间反应和接枝温度等条件的影响。对于治疗结果具有深远的意义。除了，臭氧氧化和热接枝会在某些条件下（例如在存在莫尔盐的情况下用作提高接枝率的催化剂）导致表面降解。整个研究表明，臭氧诱导的接枝是表面功能化的有力工具，尽管应该对其参数进行明智的研究和仔细选择。聚（4-苯乙烯磺酸钠）官能化提高了聚（ε-己内酯）的生物活性，同时降低了其生物降解的速度。尽管应该明智地研究和仔细选择其参数。聚（4-苯乙烯磺酸钠）官能团改善了聚（ε-己内酯）的生物活性，同时降低了其生物降解的速度。尽管应该明智地研究和仔细选择其参数。聚（4-苯乙烯磺酸钠）官能团改善了聚（ε-己内酯）的生物活性，同时降低了其生物降解的速度。