Here, an ultrasensitive non-enzymatic glucose sensor was fabricated using a facile and low price electro-deposition method. At first, thiol-functionalized magnetic nanoparticles cast onto the glassy carbon electrode (GCE) surface to provide a stable substrate with the high surface area. Then, CuO nanoparticles and Ag nanoparticles electrodeposit on the surface of Fe3O4-SH/GCE to obtain the final modified GCE. The characterization of electro-synthesized nanoparticles and the modified GCE was done by different related techniques such as field emission scanning electronic microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDX), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The proposed electrode was applied to the electrochemical sensing of glucose. By employing the optimum conditions on the preparation of modified electrode such as time and potential for electrosynthesis of two different nanoparticles, high reproducibility of measurement and sensor preparation were achieved. The thus optimized simple glucose sensor could be provided stable responses in a wide linear range from 0.06 to 1000 μM with detection limit 15 nM, indicating its potential application for real biological samples.

中文翻译：

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设计有在磁性平台上电生成的 CuO 蜂窝/Ag 纳米颗粒的纳米复合膜作为电流型葡萄糖传感器的电极

在这里，使用简便且价格低廉的电沉积方法制造了一种超灵敏的非酶葡萄糖传感器。首先，硫醇官能化的磁性纳米粒子浇铸到玻璃碳电极 (GCE) 表面上，以提供具有高表面积的稳定基材。然后，CuO纳米颗粒和Ag纳米颗粒电沉积在Fe3O4-SH/GCE表面，得到最终的改性GCE。电合成纳米颗粒和改性 GCE 的表征是通过不同的相关技术完成的，如场发射扫描电子显微镜 (FESEM)、能量色散 X 射线光谱 (EDX)、循环伏安法 (CV) 和电化学阻抗谱 (EIS) ）。所提出的电极应用于葡萄糖的电化学传感。通过采用制备修饰电极的最佳条件，例如两种不同纳米粒子的电合成时间和电位，实现了测量和传感器制备的高重现性。如此优化的简单葡萄糖传感器可以在 0.06 到 1000 μM 的宽线性范围内提供稳定的响应，检测限为 15 nM，表明其在实际生物样品中的潜在应用。