当前位置: X-MOL 学术Food Biosci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Bioactive properties of powdered peppermint and spearmint extracts: Inhibition of key enzymes linked to hypertension and type 2 diabetes
Food Bioscience ( IF 5.2 ) Pub Date : 2020-03-25 , DOI: 10.1016/j.fbio.2020.100577
Mustafa Cam , Bulent Basyigit , Hamza Alasalvar , Murat Yilmaztekin , Abdulatef Ahhmed , Osman Sagdic , Yusuf Konca , Isa Telci

Peppermint and spearmint, both members of the Lamiaceae family, have been used in the form of extracts, infusions, and decoctions, because of their health benefits. Consumers are looking for functional food products which not only provide health benefits but also necessitate less preparation time. Therefore, this study aimed to investigate the bioactive properties of powdered peppermint and spearmint extracts. Peppermint and spearmint extracts obtained using pressurized water extraction were made into powder forms with a spray dryer using the air inlet temperature of 140 °C. Powdered peppermint extract (PPE) and powdered spearmint extract (PSE) showed significant inhibition against key enzymes of type 2 diabetes (α-glucosidase) and hypertension (angiotensin 1-converting enzyme, ACE). Alpha glucosidase inhibition degree of PPE and PSE as IC50 values was 0.6 and 1.2 mg/mL, respectively, while IC50 values for the ACE inhibition test were 4.5 mg for PPE and 5.8 mg for PSE. The HPLC-DAD method for ACE inhibition activity showed the suitability of this method for plant extracts high in phenolics which had no interference effects on the results. There were no differences between PPE and PSE in the DPPH test. However, PPE had higher Trolox equivalent antioxidant capacity (190 mg/g) with the ABTS test than PSE (170 mg/g). The predominant phenolics of PPE and PSE were found to be eriocitrin (47 mg/g) and rosmarinic acid (27 mg/g), respectively.



中文翻译:

薄荷和留兰香提取物的生物活性:抑制与高血压和2型糖尿病有关的关键酶

薄荷和留兰香,都是唇形科的成员由于其有益于健康,因此已经以提取物,输液和汤的形式使用。消费者正在寻找功能性食品,这些食品不仅具有健康益处,而且需要更少的准备时间。因此,本研究旨在研究粉末状薄荷和留兰香提取物的生物活性。将使用加压水提取法获得的薄荷和留兰香提取物用喷雾干燥器以140°C的进气温度制成粉末状。薄荷粉提取物(PPE)和薄荷粉提取物(PSE)对2型糖尿病的关键酶(α-葡萄糖苷酶)和高血压(血管紧张素1转换酶ACE)具有明显的抑制作用。PPE和PSE的α葡萄糖苷酶抑制度为IC 50ACE抑制测试的IC 50值分别为0.6和1.2 mg / mL,PPE为4.5 mg,PSE为5.8 mg。HPLC-DAD方法对ACE的抑制作用表明该方法适用于高酚类植物提取物,对结果无干扰。在DPPH测试中,PPE和PSE之间没有差异。但是,在ABTS测试中,PPE的Trolox当量抗氧化能力(190 mg / g)比PSE(170 mg / g)高。发现PPE和PSE的主要酚类分别为eriocitrin(47 mg / g)和迷迭香酸(27 mg / g)。

更新日期:2020-03-25
down
wechat
bug