Herein we report our full investigation into the calcium catalyzed generation and trapping of N-acyliminium ions from readily available 3-hydroxyisoindolinones. We have successfully employed a range of traditional nucleophiles including carbon, nitrogen, and sulfur containing reactive partners. The reaction is tolerant to a wide range of functionalities and provides high value scaffolds in good to excellent yields.

中文翻译：

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钙催化N-酰基亚胺鎓离子的生成和捕集合成功能化的异吲哚啉酮

本文中，我们报告了对钙催化的生成和从易得的3-羟基异吲哚满酮中捕获N-酰基亚胺离子的全面研究。我们已经成功地使用了一系列传统的亲核试剂，包括含碳，氮和硫的反应性伙伴。该反应可耐受多种功能，并以高至优异的产率提供高价值的支架。