Abstract N’-(2-Hydroxy-4-methoxybenzylidene)isonicotinohydrazide (H2L) was used as ligand to prepare new oxidovanadium(V) complex [VOL(OMe)(MeOH)] (1) and new dioxidomolybdenum(VI) complex [MoO2L(MeOH)] (2). The two complexes were characterized on the basis of their FT-IR, UV, 1H NMR spectra, and molar conductivity. Crystal structures of 1 and 2 have been determined by single crystal X-ray diffraction techniques, which show that the hydrazone ligand coordinates as a di-valent anion with its tridentate O, N, O donors derived from the enolic and phenolic oxygen and azomethine nitrogen. The V ion in 1 is in octahedral coordination, with three donors of the hydrazone ligand and with the remaining sites furnished by one deprotonated methanol oxygen, one neutral methanol oxygen, and one oxo oxygen. The Mo ion in 2 is in octahedral coordination, with three donors of the hydrazone ligand and with the remaining sites furnished by one neutral methanol oxygen and two oxo oxygen atoms. Molecular structures of 1 and 2 are stabilized by hydrogen bonds. The hydrazone and the complexes were screened for their antimicrobial activity and showed good activity. Graphical Abstract

中文翻译：

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N'-(2-羟基-4-甲氧基亚苄基)异烟酰肼衍生的氧化钒(V)和二氧化钼(VI)配合物的合成、晶体结构和抗菌活性

摘要 以N'-(2-羟基-4-甲氧基亚苄基)异烟酰肼(H2L)为配体制备新型氧化钒(V)配合物[VOL(OMe)(MeOH)](1)和新型二氧化钼(VI)配合物[MoO2L (MeOH)] (2). 这两种配合物的特征在于它们的 FT-IR、UV、1H NMR 光谱和摩尔电导率。1 和 2 的晶体结构已通过单晶 X 射线衍射技术确定，这表明腙配体作为二价阴离子与其三齿 O、N、O 供体配位，这些供体来自烯醇和酚氧和偶氮甲碱. 1 中的 V 离子处于八面体配位，具有腙配体的三个供体，其余位点由一个去质子化的甲醇氧、一个中性甲醇氧和一个氧代氧提供。2中的Mo离子呈八面体配位，具有腙配体的三个供体，其余位点由一个中性甲醇氧和两个氧原子提供。1 和 2 的分子结构通过氢键稳定。对腙和配合物的抗微生物活性进行了筛选，并显示出良好的活性。图形概要