当前位置: X-MOL 学术Org. Chem. Front. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Palladium-catalyzed double carbonylation of propargyl amines and aryl halides to access 1-aroyl-3-aryl-1,5-dihydro-2H-pyrrol-2-ones
Organic Chemistry Frontiers ( IF 5.4 ) Pub Date : 2020-03-24 , DOI: 10.1039/d0qo00007h
Jun Ying 1, 2, 3, 4 , Zhengjie Le 1, 2, 3, 4 , Zhi-Peng Bao 1, 2, 3, 4 , Xiao-Feng Wu 1, 2, 3, 4, 5
Affiliation  

In this communication, we disclosed a palladium-catalyzed carbonylative procedure for the synthesis of 1-aroyl-3-aryl-1,5-dihydro-2H-pyrrol-2-ones from propargyl amines and aryl halides. By using TFBen as the CO source, the reaction provides a facile and straightforward access to various aryl-substituted 2-oxo-2,5-dihydropyrroles in good yields. The reaction mechanism is proven to be attractive as well.

中文翻译:

炔丙基胺和芳基卤化物的钯催化双羰基化反应,以生成1-芳基-3-芳基-1,5-二氢-2H-吡咯-2-酮

在此文中,我们公开了由炔丙基胺和芳基卤化物合成1-芳基-3-芳基-1,5-二氢-2 H-吡咯-2-酮的钯催化羰基化方法。通过使用TFBen作为CO源,该反应以高收率容易且直接地获得各种芳基取代的2-氧代-2,5-二氢吡咯。反应机理也被证明是有吸引力的。
更新日期:2020-04-24
down
wechat
bug