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The potential role of plant-derived natural products in improving arterial stiffness: A review of dietary intervention studies
Trends in Food Science & Technology ( IF 15.3 ) Pub Date : 2020-03-23 , DOI: 10.1016/j.tifs.2020.03.026
Mona Alidadi , Tannaz Jamialahmadi , Arrigo F.G. Cicero , Vanessa Bianconi , Matteo Pirro , Maciej Banach , Amirhossein Sahebkar

Background

Arterial stiffness is an early marker of cardiovascular disease. In fact, carotid-femoral pulse wave velocity, the gold standard method for the evaluation of arterial stiffness, has a positive correlation with cardiovascular events and mortality. A number of studies have shown that the consumption of different phytochemicals and plant-derived natural foods can improve arterial elasticity through various molecular mechanisms.

Scope and approach

The principal purpose of this review was to provide a summary of the clinical evidence provided by different interventional studies on the potential beneficial effects of some natural products and nutraceuticals on arterial stiffness.

Key findings and conclusions

There is evidence that some foods and food components, including cocoa flavanols, tea, watermelon, grapefruit, grape juice, berries, cherries, apples, psyllium, tomatoes, garlic, beetroot, melinja, pistachio, walnut, astaxanthin, curcumin, and safflower seeds assumption are associated with significant improvements in arterial stiffness in both healthy subjects and subjects with mildly increased cardiovascular disease risk. Further studies are needed to confirm these promising data.



中文翻译:

植物来源的天然产物在改善动脉僵硬度中的潜在作用:饮食干预研究综述

背景

动脉僵硬度是心血管疾病的早期标志。实际上,颈动脉股脉搏波速度是评估动脉僵硬度的金标准方法,与心血管事件和死亡率呈正相关。大量研究表明,食用不同的植物化学物质和植物衍生的天然食品可以通过各种分子机制改善动脉弹性。

范围和方法

这篇综述的主要目的是提供一些不同的干预研究提供的有关某些天然产物和营养保健品对动脉僵硬的潜在有益作用的临床证据的摘要。

主要发现和结论

有证据表明,某些食物和食品成分包括可可黄烷醇,茶,西瓜,葡萄柚,葡萄汁,浆果,樱桃,苹果,车前子,西红柿,大蒜,甜菜根,甜瓜,开心果,核桃,虾青素,姜黄素和红花种子该假设与健康受试者和心血管疾病风险轻度升高的受试者的动脉僵硬度显着改善有关。需要进一步的研究来确认这些有希望的数据。

更新日期:2020-03-24
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