Antimicrobial polyamide (PA) received much attention for the demand of packaging and biomedical fields. In this paper, an antimicrobial PA6 membrane was prepared via a surface chemical reaction. A highly effective antibacterial component (PHMG‐E) with terminal epoxy group was firstly synthesized via a reaction between polyhexamethylene guanidine hydrochloride (PHMG) and ethylene glycol diglycidyl ether (EGDE). Then, PHMG‐E was bonded on the surface of PA6 membrane with secondary amine reduced by borane‐tetrahydrofuran (BH₃‐THF). The antimicrobial rates of surface‐modified PA6 membrane (PA6‐PHMG) against Escherichia coli and Staphylococcus aureus were both higher than 99.99%, and the PHMG was non‐leaching due to the chemical bonding. The hydrophilicity of antibacterial PA6 membrane was also significantly improved and the mechanical performance became better.

中文翻译：

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聚六亚甲基胍盐酸盐对聚酰胺的表面抗菌改性

抗菌聚酰胺（PA）受到包装和生物医学领域需求的广泛关注。本文通过表面化学反应制备了抗菌PA6膜。首先通过聚六亚甲基胍盐酸盐（PHMG）与乙二醇二缩水甘油醚（EGDE）之间的反应合成了带有末端环氧基的高效抗菌成分（PHMG-E）。然后，PHMG-E用硼烷-四氢呋喃（BH ₃ -THF）还原的仲胺键合在PA6膜的表面。表面修饰的PA6膜（PA6-PHMG）对大肠杆菌和金黄色葡萄球菌的抗菌率均高于99.99％，并且由于化学键合，PHMG无浸出。抗菌PA6膜的亲水性也得到了显着提高，机械性能也得到改善。