The pigment of naturally colored domestic silk (NCDS) is present in the sericin layer rather than in the silk fibroin, and the color losses easily during the wet process accompanied by dissolution of the sericin. In this study, the sericin of naturally colored domestic silk was cross-linked to a water-insoluble network via treatment with a hydroxyalkyl phosphine compound, tetrakis (hydroxymethyl) phosphonium sulfate (THPS). The effects of reaction conditions, such as pH, reagent concentration, reaction temperature, and time on the cross-linking effect were investigated. Cross-linking the NCDS samples at a relatively good condition could decrease the weight loss from initial 16.7 % to less than 4.5 % during degumming. The cross-linked NCDS showed a K/S value (color depth) 1.84 times higher than the uncross-linked sample after 20 cycles of washing. The method for fixing the color of NCDS offers a kind of solution with high practicality and low cost. The cross-linker proposed in this study could also be an alternative for cross-linking sericin based materials.

天然着色的家用丝绸（NCDS）的颜料存在于丝胶蛋白层中，而不是存在于丝素蛋白中，并且在湿法过程中，伴随着丝胶蛋白的溶解，色彩容易损失。在这项研究中，通过用羟烷基膦化合物四（羟甲基）硫酸phospho（THPS）处理，将天然着色的家用丝的水溶蛋白交联到水不溶性网络上。研究了反应条件如pH，试剂浓度，反应温度和时间对交联效果的影响。在相对良好的条件下使NCDS样品交联可以使脱胶过程中的重量损失从最初的16.7％降低到小于4.5％。经过20个洗涤周期后，交联的NCDS的K / S值（色深）比未交联的样品高1.84倍。NCDS颜色的固色方法提供了一种实用性强，成本低的解决方案。这项研究中提出的交联剂也可以作为基于丝胶蛋白的材料的交联剂。