There is urgency for the development of nanomaterials that can meet emerging biomedical needs. Magnetic nanoparticles (MNPs) offer high magnetic moments and surface-area-to-volume ratios that make them attractive for hyperthermia therapy of cancer and targeted drug delivery. Additionally, they can function as contrast agents for magnetic resonance imaging (MRI) and can improve the sensitivity of biosensors and diagnostic tools. Recent advancements in nanotechnology have resulted in the realization of the next generation of MNPs suitable for these and other biomedical applications. This review discusses methods utilized for the fabrication and engineering of MNPs. Recent progress in the use of MNPs for hyperthermia therapy, controlling drug release, MRI, and biosensing is also critically reviewed. Finally, challenges in the field and potential opportunities for the use of MNPs toward improving their properties are discussed.

中文翻译：

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磁性纳米颗粒在癌症治疗和诊断中的应用。

迫切需要开发能够满足新兴生物医学需求的纳米材料。磁性纳米颗粒 (MNP) 具有高磁矩和表面积与体积比，这使其对癌症热疗和靶向药物输送具有吸引力。此外，它们还可以用作磁共振成像（MRI）的造影剂，并可以提高生物传感器和诊断工具的灵敏度。纳米技术的最新进展已经实现了适合这些和其他生物医学应用的下一代 MNP。本综述讨论了用于 MNP 制造和工程的方法。使用 MNP 进行热疗、控制药物释放、MRI 和生物传感的最新进展也受到严格审查。最后，讨论了该领域的挑战以及使用 MNP 来改善其性能的潜在机会。