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Immediate preoperative blood glucose and hemoglobin a1c levels are not predictive of postoperative infections in diabetic men undergoing penile prosthesis placement
International Journal of Impotence Research ( IF 2.6 ) Pub Date : 2020-03-20 , DOI: 10.1038/s41443-020-0261-5
Mohamad M Osman 1 , Linda M Huynh 1 , Farouk M El-Khatib 1 , Maxwell Towe 1 , Huang-Wei Su 1 , Robert Andrianne 2 , Gregory Barton 3 , Gregory Broderick 4 , Arthur L Burnett 5 , Jeffrey D Campbell 5 , Jonathan Clavell-Hernandez 6 , Jessica Connor 7 , Martin Gross 8 , Ross Guillum 6 , Amy I Guise 9 , Georgios Hatzichristodoulou 10 , Gerard D Henry 11 , Tung-Chin Hsieh 12 , Lawrence C Jenkins 13 , Christopher Koprowski 12 , Kook B Lee 14 , Aaron Lentz 3 , Ricardo M Munarriz 15 , Daniar Osmonov 16 , Shu Pan 15 , Kevin Parikh 4 , Sung Hun Park 14 , Amir S Patel 17 , Paul Perito 18 , Hossein Sadeghi-Nejad 7 , Maxime Sempels 2 , Jay Simhan 17 , Run Wang 6 , Faysal A Yafi 1
Affiliation  

Defining the risks associated with diabetes mellitus in patients undergoing penile prosthesis implantation remains controversial. Our study aims to assess whether preoperative hemoglobin a1c and preoperative blood glucose levels are associated with an increased risk for postoperative infection in diabetic men. We performed a retrospective review of 932 diabetic patients undergoing primary penile prosthesis implantation from 18 high-volume penile prosthesis implantation surgeons throughout the United States, Germany, Belgium, and South Korea. Preoperative hemoglobin a1c and blood glucose levels within 6 h of surgery were collected and assessed in univariate and multivariate models for correlation with postoperative infection, revision, and explantation rates. The primary outcome is postoperative infection and the secondary outcomes are postoperative revision and explantation. In all, 875 patients were included in the final analysis. There were no associations between preoperative blood glucose levels or hemoglobin a1c levels and postoperative infection rates; p = 0.220 and p = 0.598, respectively. On multivariate analysis, a history of diabetes-related complications was a significant predictor of higher revision rates (p = 0.034), but was nonsignificant for infection or explantation rates. We conclude preoperative blood glucose levels and hemoglobin a1c levels are not associated with an increased risk for postoperative infection, revision, or explantation in diabetic men undergoing penile prosthesis implantation.



中文翻译:

术前即刻血糖和血红蛋白 a1c 水平不能预测接受阴茎假体放置的糖尿病男性术后感染

在阴茎假体植入患者中确定与糖尿病相关的风险仍然存在争议。我们的研究旨在评估术前血红蛋白 a1c 和术前血糖水平是否与糖尿病男性术后感染风险增加有关。我们对来自美国、德国、比利时和韩国的 18 位高容量阴茎假体植入外科医生的 932 名接受原发性阴茎假体植入的糖尿病患者进行了回顾性研究。收集术前血红蛋白 a1c 和手术后 6 小时内的血糖水平,并在单变量和多变量模型中评估与术后感染、翻修和外植率的相关性。主要结果是术后感染,次要结果是术后翻修和外植。总共有 875 名患者被纳入最终分析。术前血糖水平或血红蛋白 a1c 水平与术后感染率之间没有关联;p  = 0.220 和p  = 0.598,分别。在多变量分析中,糖尿病相关并发症病史是较高翻修率的重要预测因素 ( p  = 0.034),但对感染或移植率无显着意义。我们得出结论,术前血糖水平和血红蛋白 a1c 水平与接受阴茎假体植入的糖尿病男性术后感染、翻修或外植风险增加无关。

更新日期:2020-04-24
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