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Delay activity in the Wulst of pigeons (Columba livia) represents correlates of both sample and reward information.
Neurobiology of Learning and Memory ( IF 2.7 ) Pub Date : 2020-03-20 , DOI: 10.1016/j.nlm.2020.107214
Catrona Anderson 1 , Melissa Johnston 1 , Ethan J Marrs 1 , Blake Porter 1 , Michael Colombo 1
Affiliation  

The avian Wulst is the pallial (analogous to mammalian cortex) termination point of the thalamofugal pathway, one of two main visual pathways in birds, and is considered to be equivalent to primate striate cortex. We recorded neuronal activity from the Wulst in pigeons during two versions of a delayed matching-to-sample procedure. Two birds were trained on a common outcomes (CO) procedure, in which correct responses following both the skateboarder and the flower stimuli were associated with reward. Two other birds were trained on a differential outcomes (DO) procedure in which correct responses following only the skateboarder stimulus were associated with reward, while correct responses following the flower stimulus were not rewarded. In line with previous studies, under CO conditions, and for both excitatory and inhibitory neurons, delay activity in the Wulst was significantly different from baseline activity following both sample stimuli, which may indicate that Wulst delay activity is a neural correlate of working memory for the sample stimulus. On the other hand, under DO conditions, Wulst delay activity appeared to be a neural correlate of the upcoming reward. We argue that Wulst neurons display flexibility in their encoding in that they can encode both sample and reward information, but may default to one type of coding over the other based on the demands of the task. The current study provides the first evidence that delay activity in the Wulst represents both a neural correlate for sample information as well as reward information.

中文翻译:

鸽子的伍尔斯塔(Wulst)的延迟活动代表了样本和奖励信息的相关性。

鸟类的沃尔斯特(Walst)是丘脑-真菌途径的丘脑末端(类似于哺乳动物的皮质),是鸟类的两种主要视觉途径之一,被认为等同于灵长类的纹状皮质。我们在两个版本的延迟匹配采样过程中记录了鸽子的伍尔斯特神经元活动。两只鸟接受了共同结果(CO)程序的训练,其中滑板手和花朵刺激后的正确反应都与奖励相关联。对另外两只鸟进行了差异结果(DO)程序的训练,其中仅滑板手刺激后的正确反应与奖励相关,而花刺激后的正确反应未得到奖励。与先前的研究一致,在CO条件下,对于兴奋性和抑制性神经元,两种样品刺激后,Wulst的延迟活动与基线活动显着不同,这可能表明Wulst延迟活动是样品刺激的工作记忆的神经相关因素。另一方面,在溶解氧条件下,沃尔斯特延迟活动似乎是即将到来的奖赏的神经关联。我们认为,沃尔斯特神经元在编码方面显示出灵活性,因为它们既可以对样本信息也可以对奖励信息进行编码,但是根据任务的要求,它们可能默认为一种编码类型,而不是另一种类型。当前的研究提供了第一个证据,即伍尔斯特的延迟活动既代表了样本信息的神经关联,也代表了奖励信息。这可能表明沃尔斯特延迟活动是样本刺激的工作记忆的神经相关因素。另一方面,在溶解氧条件下,沃尔斯特延迟活动似乎是即将到来的奖赏的神经关联。我们认为,沃尔斯特神经元在编码方面显示出灵活性,因为它们既可以对样本信息也可以对奖励信息进行编码,但是根据任务的要求,它们可能默认为一种编码类型,而不是另一种类型。当前的研究提供了第一个证据,即伍尔斯特的延迟活动既代表了样本信息的神经关联,也代表了奖励信息。这可能表明沃尔斯特延迟活动是样本刺激的工作记忆的神经相关因素。另一方面,在溶解氧条件下,沃尔斯特延迟活动似乎是即将到来的奖赏的神经关联。我们认为,沃尔斯特神经元在编码方面显示出灵活性,因为它们既可以对样本信息也可以对奖励信息进行编码,但是根据任务的要求,它们可能默认为一种编码类型,而不是另一种类型。当前的研究提供了第一个证据,即伍尔斯特的延迟活动既代表了样本信息的神经关联,也代表了奖励信息。我们认为,沃尔斯特神经元在编码方面显示出灵活性,因为它们既可以对样本信息也可以对奖励信息进行编码,但是根据任务的要求,它们可能默认为一种编码类型,而不是另一种类型。当前的研究提供了第一个证据,即伍尔斯特的延迟活动既代表了样本信息的神经关联,也代表了奖励信息。我们认为,沃尔斯特神经元在编码方面显示出灵活性,因为它们既可以对样本信息也可以对奖励信息进行编码,但是根据任务的要求,它们可能默认为一种编码类型,而不是另一种类型。当前的研究提供了第一个证据,即伍尔斯特的延迟活动既代表了样本信息的神经关联,也代表了奖励信息。
更新日期:2020-03-21
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