Various traditional edible fungi were demonstrated to modulate gut microbiota. In this study, ¹H NMR and high-throughput sequencing were used to investigate the difference of microecology modulating function between Ophicordyceps sinensis and Cordyceps militaris. The data showed that total 7 constituents (glucose, mannitol, trehalose, aspartate, glutamate, lysine, threonine) were selected as potential biomarkers to identify O. sinensis and C. militaris based on ¹H NMR. After in vitro fermentation, both O. sinensis and C. militaris modulated gut microbiota composition, via decreasing the ratio of Firmicutes to Bacteroidetes. However, O. sinensis could significantly decreased the pH and stimulated the production of short-chain fatty acids versus C. militaris. O. sinensis also increased the relative abundance of probiotics including Phascolarctobacterium and Bifidobacterium. In general, the results suggested that O. sinensis had more positive effects on gut microbiota compared with C. militaris, which was conducive to the development of functional products of traditional edible fungi.

各种传统的食用真菌被证明可以调节肠道菌群。在这项研究中，¹ H NMR和高通量测序被用来研究微生态调节功能在中华phi虫草和Cord虫草之间的差异。数据显示，总共选择了7种成分（葡萄糖，甘露醇，海藻糖，天冬氨酸，谷氨酸，赖氨酸，苏氨酸）作为识别O的潜在生物标记。冬虫夏草和Ç。基于¹ H NMR的军事行动。后在体外发酵，既Ò。冬虫夏草和Ç。蛹虫草调制肠道微生物组合物，通过降低的比率厚壁菌门到拟杆菌。但是，O。中华绒螯蟹可显着降低pH值，并刺激短链脂肪酸相对于C的产生。军国主义。Ø。中华also还增加了包括杆菌属细菌和双歧杆菌在内的益生菌的相对含量。在一般情况下，结果表明，Ö。冬虫夏草有较对肠道菌群产生更积极效果Ç。军国主义，有利于传统食用菌功能产品的开发。