A new colorimetric and fluorescent probe 2 for SO₃²⁻/HSO₃^‒ detection was developed based on a conjugated benzothiazole derivative. The probe 2 was red color in aqueous solution and became colorless in the presence of SO₃²⁻/HSO₃^‒, accompanied by a fluorescence quenching. It was rationalized by an intramolecular charge transfer (ICT) mechanism, where the addition of SO₃²⁻/HSO₃^‒ to the vinyl double bond broken the conjugation and blocked the ICT process. This probe showed highly selective detection of SO₃²⁻/HSO₃^‒ compared with other sulfur-containing species and featured a detection limit of 2.01 μM. Moreover, the present probe was also successfully used for the fluorescence imaging of intracellular sulfur dioxide derivatives in living HeLa cells.

基于共轭苯并噻唑衍生物，开发了一种用于SO ₃ ^2- / HSO ₃ ^‒检测的比色和荧光探针2。探头2是红色在水溶液中和在SO的存在下变成无色₃ ^2- / HSO ₃ ^- ，伴随荧光猝灭。它是由一个分子内电荷转移（ICT）机构，其中的SO的添加合理化₃ ^{2- /} HSO ₃ ^-于乙烯基双键断裂共轭并阻止ICT过程。该探针显示出对SO ₃ ^2- / HSO的高度选择性检测₃ ^-与其他含硫物质相比和特色2.01μM的检测限。而且，本发明的探针还成功地用于活HeLa细胞中细胞内二氧化硫衍生物的荧光成像。