当前位置: X-MOL 学术Diabetes Care › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Daniel Porte Jr.: A Leader in Our Understanding of the Role of Defective Insulin Secretion and Action in Obesity and Type 2 Diabetes
Diabetes Care ( IF 16.2 ) Pub Date : 2020-04-01 , DOI: 10.2337/dci19-0068
Jerry P. Palmer 1, 2 , Steven E. Kahn 1, 2 , Michael W. Schwartz 2 , Gerald J. Taborsky 1, 2 , Stephen C. Woods 3
Affiliation  

Daniel Porte Jr. was born in New York City in 1931, and with his father being a clinical cardiologist, medicine was part of his life from very early on. After completing his undergraduate studies at Brown University, he commenced his migration west by first attending medical school at the University of Chicago, where he graduated with honors in 1957. Completing his westward migration, Dan moved to San Francisco for his internship and residency training in medicine in the University of California system. During that time, he spent 2 years performing research with Richard Havel at the Cardiovascular Research Institute at the University of California, San Francisco. It was during this period that Dan published his first scientific article describing cholesterol-labeled lipoproteins as a tracer for examining the fate of plasma cholesterol (1), as well as a clinical research study of an unusual patient with McArdle syndrome causing defective muscle phosphorylase leading to defective exercise tolerance (2). Daniel Porte Jr. at medical school graduation, University of Chicago, 1957 Based on this early experience, it became clear to Dan that his future lay in academia and clinical research, so he decided to travel north to the University of Washington (UW) in Seattle for fellowship training in endocrinology and metabolism. One of the academic attractants at the time was Robert H. Williams, who was a leading national force in endocrinology and Chairman of Medicine at UW. As lipids were an important area of investigation in Seattle as well as in San Francisco at the time, Dan continued to work in this area during his fellowship and early faculty years. Following the development of the insulin radioimmunoassay, however, a whole new field opened up and he moved his research in a completely new direction. Dan commenced his research in glucose metabolism and diabetes …

中文翻译:

小丹尼尔·波特(Daniel Porte Jr.):了解肥胖和2型糖尿病中胰岛素的不良分泌和作用的作用的领导者

小丹尼尔·波特(Daniel Porte Jr.)于1931年出生于纽约市,他的父亲是一名临床心脏病专家,从很早就开始从事医学。在布朗大学完成大学学业后,他首先在芝加哥大学医学院就读,并于1957年以优异的成绩毕业,开始了向西的迁移。加州大学系统医学。在那段时间里,他花了2年的时间与旧金山大学加利福尼亚大学心血管研究所的Richard Havel进行研究。在此期间,Dan发表了他的第一篇科学文章,该文章描述了胆固醇标记的脂蛋白作为追踪血浆胆固醇命运的示踪剂(1),以及一项针对McArdle综合征的异常患者导致肌肉磷酸化酶缺陷导致运动耐力缺陷的临床研究(2)。小丹尼尔·波特(Daniel Porte Jr.)于1957年在芝加哥大学医学院毕业时,根据这一早期经验,丹逐渐意识到他的未来取决于学术界和临床研究,因此他决定北上华盛顿大学(UW)。西雅图接受内分泌和新陈代谢方面的进修培训。罗伯特·威廉姆斯(Robert H. Williams)是当时的学术吸引人之一,他是内分泌学方面的领先国家力量,也是华盛顿大学的医学主席。由于脂质是当时西雅图和旧金山的重要研究领域,因此Dan在他的进修和任职初期一直在这一领域工作。然而,随着胰岛素放射免疫测定法的发展,一个崭新的领域打开了,他将研究朝着全新的方向发展。Dan开始从事葡萄糖代谢和糖尿病的研究……
更新日期:2020-03-21
down
wechat
bug