The effect of spray‐dried porcine plasma (SDPP) on the intestinal histological organization and autochthonous microbiota composition was evaluated in Sparus aurata. Fish were fed a basal diet (51 g/kg protein, 17 g/kg fat, 20.6 MJ/kg gross energy) and a diet containing 3 g/kg SDPP for 95 days (initial body weight, BW = 9.5 ± 0.2g, mean ± SD). The inclusion of SDPP promoted growth (p .05) between both groups. Intestinal microbiota was dominated by Proteobacteria (>85%) and Firmicutes (5%–12%), whereas Bacteroidetes never represented more than 1.5%. γ‐Proteobacteria, and Bacilli and Clostridia were the predominant classes. The short administration of SDPP (20 days) resulted in changes in microbiota diversity and richness associated with an increase in the sequences of the genus Lactobacillus and to a decrease in the genus Vibrio, whereas these changes were reverted at 95 days. Intestinal goblet cell density was not correlated to microbiota diversity and richness changes rather than to the immunostimulatory effect of the SDPP.

中文翻译：

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喷雾干燥猪血浆对金头鲷（Sparus aurata）肠道微生物群的影响

在 Sparus aurata 中评估了喷雾干燥猪血浆 (SDPP) 对肠道组织学和本土微生物群组成的影响。给鱼喂食基础日粮（51 g/kg 蛋白质、17 g/kg 脂肪、20.6 MJ/kg 总能量）和含有 3 g/kg SDPP 的日粮 95 天（初始体重，BW = 9.5 ± 0.2g，平均值±标准差）。SDPP 的加入促进了两组之间的增长 (p < .05)。肠道微生物群主要由变形菌 (>85%) 和厚壁菌门 (5%–12%) 主导，而拟杆菌门从未超过 1.5%。γ-变形杆菌、杆菌和梭状芽孢杆菌是主要类别。SDPP 的短期给药（20 天）导致微生物群多样性和丰富度的变化，与乳酸杆菌属序列的增加和弧菌属的减少相关，而这些变化在 95 天时恢复。肠道杯状细胞密度与微生物群多样性和丰富度变化无关，而与 SDPP 的免疫刺激作用无关。