ABSTRACT This study was conducted to investigate the effects of composited functional bioactive substances on the growth performance and immune function of growth retardation (GR) pigs. Twenty-four 42-day-old GR pigs were fed with basal diet containing 0 or 0.5% composited functional bioactive substances package (FP) for 21 days. The results showed that dietary supplementation with FP decreased feed:gain ratio, increased the relative and absolute weight of the liver (P < 0.05). Supplementation with FP decreased serum alkaline phosphatase and malondialdehyde, but increased aspartic acid, cysteine, arginine, proline and taurine concentrations, as well as serum superoxide dismutase and catalase activities (p < 0.05). FP treatment increased all determined cytokines (IL-1β, IL-4, IL-6, IL-8, IL-10, IL-12, GM-CSF, IFN-γ, TGF-β1, TNF-α) concentrations in serum compared with the control treatment (p < 0.05). These findings indicate that functional bioactive substances can improve feed conversion rate, serum anti-oxidant capacity and immunity and can be as effective growth promoter in the GR piglets.

中文翻译：

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功能性生物活性物质提高生长迟缓猪的生长性能、抗氧化能力和免疫功能

摘要 本研究旨在研究复合功能性生物活性物质对生长迟缓 (GR) 猪生长性能和免疫功能的影响。用含有 0 或 0.5% 复合功能性生物活性物质包 (FP) 的基础日粮喂养 24 头 42 天大的 GR 猪 21 天。结果表明，日粮中添加 FP 降低了料重比，增加了肝脏的相对和绝对重量（P < 0.05）。补充 FP 会降低血清碱性磷酸酶和丙二醛，但会增加天冬氨酸、半胱氨酸、精氨酸、脯氨酸和牛磺酸的浓度，以及血清超氧化物歧化酶和过氧化氢酶的活性（p < 0.05）。FP 治疗增加了所有确定的细胞因子（IL-1β、IL-4、IL-6、IL-8、IL-10、IL-12、GM-CSF、IFN-γ、TGF-β1、与对照治疗相比，血清中的 TNF-α) 浓度 (p < 0.05)。这些发现表明，功能性生物活性物质可以提高饲料转化率、血清抗氧化能力和免疫力，可以作为GR仔猪的有效生长促进剂。