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Construction of a novel "ball-and-rod" MSNs-pp-PEG system: a promising antitumor drug delivery system with a particle size switchable function.
Chemical Communications ( IF 4.9 ) Pub Date : 2020-04-30 , DOI: 10.1039/d0cc00600a Xin He 1 , Dong Wang , Peng Chen , Youbei Qiao , Tiehong Yang , Zhe Yu , Chaoli Wang , Hong Wu
Chemical Communications ( IF 4.9 ) Pub Date : 2020-04-30 , DOI: 10.1039/d0cc00600a Xin He 1 , Dong Wang , Peng Chen , Youbei Qiao , Tiehong Yang , Zhe Yu , Chaoli Wang , Hong Wu
Affiliation
To utilize the advantages of drug carriers of different sizes, a size switchable "ball-and-rod" drug delivery system was constructed, which could switch its size in response to enzymes in tumors. It would be a promising system with long circulation and deep penetration properties, which enable its application in tumor treatment.
中文翻译:
新型“球杆” MSNs-pp-PEG系统的构建:具有粒径可切换功能的有前途的抗肿瘤药物递送系统。
为了利用不同大小的药物载体的优势,构建了大小可切换的“球杆”药物递送系统,该系统可以响应肿瘤中的酶来改变其大小。这将是一个有希望的系统,具有长循环和深穿透特性,使其能够在肿瘤治疗中应用。
更新日期:2020-03-20
中文翻译:
新型“球杆” MSNs-pp-PEG系统的构建:具有粒径可切换功能的有前途的抗肿瘤药物递送系统。
为了利用不同大小的药物载体的优势,构建了大小可切换的“球杆”药物递送系统,该系统可以响应肿瘤中的酶来改变其大小。这将是一个有希望的系统,具有长循环和深穿透特性,使其能够在肿瘤治疗中应用。