This study developed a computational fluid dynamics (CFD) model to assess the impact of the site of location of a commercial device (HEPA filter/ultraviolet light) on its capacity for microbial decontamination of indoor air. The three locations of the air decontamination device (ADD) in the aerobiology chamber were at the center, the middle of one of the lateral sides, and at the middle of the side in front of the axial air circulating fan. The findings were then compared to the experimental data generated in an earlier study on the same device using aerosolized Staphylococcus aureus as the challenge. The findings of the CFD model were strongly correlated to the experimental results, and the best site for the ADD was found to be at the middle of one of the lateral sides of the chamber. In this state, the microbial decontamination efficiency of the ADD was 99.46%. Additionally, this modeling study identified (a) the device’s optimal location in the chamber for microbial decontamination and the device’s effectiveness, (b) the axial fan’s location and its ability to uniformly distribute the airborne bacteria inside the chamber, and (c) suitability of the air samples collecting from the chamber’s center. The incorporation of this model could boost the design and construction of the chamber, reduce the need for laboratory experimentation, and also help to simulate and investigate an ADD’s efficacy for maximum reduction of airborne pathogens.

中文翻译：

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空气生物学室内空气净化装置的分析：数值实验研究

本研究开发了一种计算流体动力学 (CFD) 模型，以评估商业设备（HEPA 过滤器/紫外线）的位置对其室内空气微生物净化能力的影响。空气净化器（ADD）在空气生物舱内的三个位置分别位于中央、侧面之一的中间和轴流空气循环风机前侧的中间。然后将这些发现与使用雾化金黄色葡萄球菌作为挑战在同一设备上进行的早期研究中产生的实验数据进行比较。CFD 模型的发现与实验结果密切相关，并且发现 ADD 的最佳位置位于腔室侧面之一的中间。在这种状态下，ADD的微生物净化效率为99.46%。此外，该建模研究确定了 (a) 设备在微生物净化室中的最佳位置和设备的有效性，(b) 轴流风扇的位置及其在室内均匀分布空气传播细菌的能力，以及 (c)从腔室中心收集的空气样本。该模型的结合可以促进腔室的设计和构造，减少对实验室实验的需求，还有助于模拟和研究 ADD 最大程度减少空气传播病原体的功效。(b) 轴流风扇的位置及其在腔室内均匀分布空气传播细菌的能力，以及 (c) 从腔室中心收集的空气样本的适用性。该模型的结合可以促进腔室的设计和构造，减少对实验室实验的需求，还有助于模拟和研究 ADD 最大程度减少空气传播病原体的功效。(b) 轴流风扇的位置及其在腔室内均匀分布空气传播细菌的能力，以及 (c) 从腔室中心收集的空气样本的适用性。该模型的结合可以促进腔室的设计和构造，减少对实验室实验的需求，还有助于模拟和研究 ADD 最大程度减少空气传播病原体的功效。