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Evaluation of chelating and cytoprotective activity of vanillin against the toxic action of mercuric chloride as an alternative for phytoremediation
Environmental Geochemistry and Health ( IF 4.2 ) Pub Date : 2020-03-04 , DOI: 10.1007/s10653-020-00538-x
Joelma P. da Silva , Maria do S. Costa , Fabia F. Campina , Camila F. Bezerra , Thiago S. de Freitas , Amanda K. Sousa , Celestina E. Sobral Souza , Yedda M. L. S. de Matos , Francisco N. Pereira-Junior , Irwim R. A. Menezes , Henrique D. M. Coutinho , Janaína E. Rocha

Mercury is widely found in nature, however, in low concentrations, but anthropological activities have increased its concentration considerably. This causes various environmental hazards and human health. Many substances are capable of reversing the toxicity of mercuric chloride in the environment. The aim of the present study was to determine the chelating effect of vanillin, as well as to evaluate its capacity for cytoprotection in prokaryotic and eukaryotic plant models. Chelating activity was determined from vanillin’s ability to reduce iron III ions. To evaluate cytoprotection in a unicellular prokaryotic and eukaryotic model, Escherichia coli and Candida albicans, respectively, were used. And to evaluate the cytoprotective activity in vegetables, lettuce seeds were submitted to different concentrations of mercuric chloride and its association with the sub-allelopathic concentration of vanillin (32 µg/mL). Vanillin has been found to have antioxidant activity as it can reduce iron III ions. The use of vanillin also allows for better growth and development of Lactuca sativa seed root and stem, also allowing better preservation of its biochemical structures. These results are quite important, as environmental contamination by heavy metals has increased dramatically and finding a viable alternative to grow vegetables in contaminated areas is very valid.



中文翻译:

评估香兰素对氯汞的毒性作用的螯合和细胞保护活性,以作为植物修复的替代方法

汞在自然界中被广泛发现,但是浓度很低,但是人类活动大大增加了汞的浓度。这导致各种环境危害和人类健康。许多物质都能够逆转环境中氯化汞的毒性。本研究的目的是确定香兰素的螯合作用,并评估其在原核和真核植物模型中的细胞保护能力。螯合活性由香草醛还原铁III离子的能力决定。若要评估单细胞原核和真核模型,大肠杆菌白色念珠菌中的细胞保护。分别使用。为了评估蔬菜中的细胞保护活性,将莴苣种子置于不同浓度的氯化汞中,并将其与香兰素的亚化感作用浓度(32 µg / mL)联系起来。香兰素已被发现具有抗氧化活性,因为它可以还原三价铁离子。香兰素的使用还可以使紫花苜蓿种子的根和茎更好地生长和发育,还可以更好地保存其生化结构。这些结果非常重要,因为重金属对环境的污染急剧增加,在受污染的地区找到可行的蔬菜种植替代品是非常有效的。

更新日期:2020-04-21
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