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Mercury in Marine, Freshwater and Aquaculture Species from South India and Human Exposure Risk Assessment
Exposure and Health ( IF 6.7 ) Pub Date : 2020-03-13 , DOI: 10.1007/s12403-020-00352-x
K. L. Subhavana , R. T. Keerthana , Asif Qureshi

We report concentrations of methylmercury (MeHg) and total mercury (THg) in marine, freshwater and aquaculture species from a major fisheries landing center in the east coast of India, Nellore. Concentrations of MeHg were in the range 1.67–105.25 ng/g ww (wet weight). Aquaculture species had lower mercury concentrations than naturally caught marine or freshwater species (p < 0.05). While none of the 242 analyzed samples had MeHg greater than the limits stipulated by food and safety authority in India (250 ng/g) or other countries, dietary exposure analysis for a subsistence fish consuming Indian population for which fish consumption patterns were known revealed that there was a 14.3% probability of exceedance of the US EPA reference dose of 0.1 µg/kg BW/day. The US EPA one-box pharmacokinetic model slightly better predicts the observed hair mercury concentrations in this population when the MeHg absorption efficiency in the human gastrointestinal tract is 1–72% (with a median of 14%) as suggested recently rather than the 91–97% used more commonly.



中文翻译:

南印度海洋,淡水和水产养殖物种中的汞和人类暴露风险评估

我们报告了印度东海岸的一个主要渔业登陆中心内洛尔的海洋,淡水和水产养殖种类中甲基汞(MeHg)和总汞(THg)的浓度。MeHg的浓度范围为1.67–105.25 ng / g ww(湿重)。水产养殖物种的汞浓度低于自然捕获的海洋或淡水物种(p <0.05)。尽管242个分析样品中的MeHg均未超过印度或其他国家食品和安全部门规定的限值(250 ng / g),但对已知鱼类消费方式的低消费鱼类印度种群的膳食暴露分析表明:超过美国EPA参考剂量0.1 µg / kg体重/天的可能性为14.3%。如最近建议的那样,当在人体胃肠道中MeHg的吸收效率为1-72%(中位数为14%)时,美国EPA的一盒药代动力学模型可以更好地预测该人群中观察到的头发汞浓度,而不是91- 97%更常用。

更新日期:2020-04-21
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