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A concise review of microfluidic particle manipulation methods
Microfluidics and Nanofluidics ( IF 2.8 ) Pub Date : 2020-03-19 , DOI: 10.1007/s10404-020-2328-5
Shuaizhong Zhang , Ye Wang , Patrick Onck , Jaap den Toonder

Particle manipulation is often required in many applications such as bioanalysis, disease diagnostics, drug delivery and self-cleaning surfaces. The fast progress in micro- and nano-engineering has contributed to the rapid development of a variety of technologies to manipulate particles including more established methods based on microfluidics, as well as recently proposed innovative methods that still are in the initial phases of development, based on self-driven microbots and artificial cilia. Here, we review these techniques with respect to their operation principles and main applications. We summarize the shortcomings and give perspectives on the future development of particle manipulation techniques. Rather than offering an in-depth, detailed, and complete account of all the methods, this review aims to provide a broad but concise overview that helps to understand the overall progress and current status of the diverse particle manipulation methods. The two novel developments, self-driven microbots and artificial cilia-based manipulation, are highlighted in more detail.



中文翻译:

简要综述微流控颗粒处理方法

在许多应用中,例如生物分析,疾病诊断,药物输送和自清洁表面,经常需要进行颗粒处理。微观和纳米工程学的飞速发展促进了多种技术的发展,包括基于微流体的成熟方法以及最近仍处于开发初期的创新方法,这些技术可用于处理颗粒。自驱动微型机器人和人造纤毛。在这里,我们就这些技术的操作原理和主要应用进行了回顾。我们总结了缺点,并就粒子操纵技术的未来发展给出了看法。与其提供所有方法的深入,详细和完整的说明,这篇综述旨在提供一个广泛而简洁的概述,以帮助了解各种粒子处理方法的总体进展和当前状态。两种新颖的开发,即自动驱动的微型机器人和基于人工纤毛的操纵,将更加详细地介绍。

更新日期:2020-04-22
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