Arylnaphthalene compounds, also called cyclolignolides, are lignans and have been extensively studied and documented, especially podophyllotoxin and its derivatives. Great progress has been made in phytochemical studies on arylnaphthalenes in the last 20 years (1999–2019), and arylnaphthalenes have been reported to have various biological activities. A total of 338 new arylnaphthalene compounds from over 60 families, including Acanthaceae, Phyllanthaceae, Lamiaceae, Lauraceae, Schisandraceae, Berberidaceae, and Boraginaceae, have been discovered. This paper will highlight their structural features, sources, and biological activities and briefly discuss their structure–activity relationships.

芳基萘化合物，也称为环木酚内酯，是木脂素，并且已经被广泛研究和记录，尤其是鬼臼毒素及其衍生物。在过去的20年中（1999-2019年），芳基萘的植物化学研究取得了巨大进展，据报道芳基萘具有多种生物活性。共发现了来自60多个科的338种新的芳基萘化合物，包括棘皮科，毛兰科，唇形科，月桂科，五味子科，小ber科和紫草科。本文将重点介绍它们的结构特征，来源和生物活性，并简要讨论它们的结构-活性关系。