Abstract Objectives To synthesize experimental orthodontic resins used for bracket bonding containing different concentrations of niobophosphate (NbG) and 45S5 glasses. Methods Experimental resins (Bis-GMA + UDMA + DMAEMA) were developed with two bioactive glasses (NbG and 45S5) in concentrations of 5, 10 and 20 (wt%). An experimental resin without glass and a commercial resin (Transbond XT) were used. Control of pH and ions release (calcium and phosphate) at different pH values (4 and 7) were evaluated in the time intervals of 24 h, 7 d, 14 d and 28 d. Microhardness, bioactivity (SEM, FTIR/ATR) and antibacterial activity of the resins were analyzed. Metal brackets were bonded to premolars (n = 10) with the resins to evaluate shear bond strength (SBS). Results The experimental resins containing 45S5 were capable of raising the pH of the solution and showed high values of calcium and phosphate ions release. Resins containing NbG had a neutralizing potential. The NbG and Transbond resins released only phosphate ions. Transbond XT showed high microhardness values when compared with the experimental 45S5 resins (p 0,05). The resins with presence of bioactive particles showed antibacterial activity. Conclusion Without compromising the shear bond strength, bioactive glasses showed the capacity to elevate pH, reduce the hardness of experimental resins when compared with Transbond XT and no filler experimental resin.

中文翻译：

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含生物活性玻璃的正畸树脂：制备、理化特性、抗菌活性、生物活性和与牙釉质的结合

摘要 目的合成含不同浓度的铌磷酸盐(NbG) 和45S5 玻璃的用于托槽粘接的实验性正畸树脂。方法 用两种生物活性玻璃（NbG 和 45S5）开发实验树脂（Bis-GMA + UDMA + DMAEMA），浓度分别为 5、10 和 20（wt%）。使用不含玻璃的实验树脂和商业树脂 (Transbond XT)。在 24 小时、7 天、14 天和 28 天的时间间隔内评估了在不同 pH 值（4 和 7）下对 pH 和离子释放（钙和磷酸盐）的控制。分析了树脂的显微硬度、生物活性（SEM、FTIR/ATR）和抗菌活性。用树脂将金属托槽与前磨牙 (n = 10) 粘合以评估剪切粘合强度 (SBS)。结果 含有 45S5 的实验树脂能够提高溶液的 pH 值，并显示出较高的钙离子和磷酸根离子释放值。含有 NbG 的树脂具有中和潜力。NbG 和 Transbond 树脂仅释放磷酸根离子。与实验性 45S5 树脂相比，Transbond XT 显示出较高的显微硬度值 (p = 0.05)。存在生物活性颗粒的树脂显示出抗菌活性。结论 在不影响剪切粘合强度的情况下，与 Transbond XT 和无填料实验树脂相比，生物活性玻璃显示出提高 pH 值、降低实验树脂硬度的能力。与实验性 45S5 树脂相比，Transbond XT 显示出较高的显微硬度值 (p = 0.05)。存在生物活性颗粒的树脂显示出抗菌活性。结论 在不影响剪切粘合强度的情况下，与 Transbond XT 和无填料实验树脂相比，生物活性玻璃显示出提高 pH 值、降低实验树脂硬度的能力。与实验用 45S5 树脂相比，Transbond XT 显示出较高的显微硬度值 (p 0.05)。存在生物活性颗粒的树脂显示出抗菌活性。结论 在不影响剪切粘合强度的情况下，与 Transbond XT 和无填料实验树脂相比，生物活性玻璃显示出提高 pH 值、降低实验树脂硬度的能力。